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科研机构
上海药物研究所 [30]
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期刊论文 [30]
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2021 [3]
2020 [1]
2018 [3]
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Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Liang, Xiaoying
;
Lan, Yuan
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/11/04
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407
作者:
Li, Zhiqiang
;
Li, Xinzhi
;
Su, Ming-Bo
;
Gao, Li-Xin
;
Zhou, Yu-Bo
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Radix Paeoniae Alba increases serum estrogen level and up-regulates estrogen receptor expression in uterus and vagina of immature/ovariectomized mice
期刊论文
Phytotherapy research : PTR, 2018
作者:
Xu, Ying
;
Li, Xin
;
Chen, Ting
;
Qu, Ya-Kun
;
Zheng, Hong-Xia
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  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Lower genomic stability of induced pluripotent stem cells reflects increased non-homologous end joining
期刊论文
CANCER COMMUNICATIONS, 2018, 卷号: 38
作者:
Zhang, Minjie
;
Wang, Liu
;
An, Ke
;
Cai, Jun
;
Li, Guochao
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
Genomic stability
DNA damage repair
iPSCs
ESCs
Testosterone-induced benign prostatic hyperplasia rat and dog as facile models to assess drugs targeting lower urinary tract symptoms
期刊论文
PLOS ONE, 2018, 卷号: 13, 期号: 1
作者:
Li, Jing
;
Tian, Yanxin
;
Guo, Shimeng
;
Gu, Haifeng
;
Yuan, Qianting
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 8, 页码: 1104-1119
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
LX2343
cognitive deficits
oxidative stress
tauopathy
mitochondria
GSK-3 beta inhibitor
neuroprotection
ICV-STZ rats
Norditerpenoids and Dinorditerpenoids from the Seeds of Podocarpus nagi as Cytotoxic Agents and Autophagy Inducers
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 7, 页码: 2110-2117
作者:
Feng, Zhe-Ling
;
Zhang, Le-Le
;
Zheng, Yuan-Dong
;
Liu, Qian-Yu
;
Liu, Jing-Xin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Peptide-Tethered Hydrogel Scaffold Promotes Recovery from Spinal Cord Transection via Synergism with Mesenchymal Stem Cells
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 4, 页码: 3330-3342
作者:
Li, Li-Ming
;
Han, Min
;
Jiang, Xin-Chi
;
Yin, Xian-Zhen
;
Chen, Fu
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
hyaluronic acid
hydrogel scaffold
mesenchymal stem cells
adhesive peptide
spinal cord injury
tissue engineering
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