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科研机构
兰州大学 [10]
内容类型
期刊论文 [10]
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2016 [1]
2014 [2]
2013 [2]
2012 [4]
2009 [1]
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pharmacol... [10]
biochemist... [1]
research &... [1]
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Synthesis, biological activities and structure-activity relationships for new avermectin analogues
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 121, 页码: 422-432
作者:
Zhang, J
;
Nan, X
;
Yu, HT
;
Cheng, PL
;
Zhang, Y
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/01/11
Avermectin
Structural modifications
Insecticidal activities
QSAR analysis
Synthesis and structure-activity relationship of nuciferine derivatives as potential acetylcholinesterase inhibitors
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 6
-
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  |  
浏览/下载:4/0
  |  
提交时间:2014/12/05
Aporphine alkaloids
Acetylcholinesterase inhibitors
Structure-activity relationships
Evaluation of insecticidal activity of camptothecin analogs against Brontispa longissima
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2014, 卷号: 23, 期号: 2, 页码: 980-986
作者:
Yang, L
;
Zhang, ZJ
;
Liu, YQ
;
Zhao, CY
;
Wang, MJ
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  |  
浏览/下载:3/0
  |  
提交时间:2015/12/29
Camptothecin
Insecticidal activity
Brontispa longissima
Structure-activity relationships
Synthesis and Structure-Activity Relationships of N-Methyl-5,6,7-trimethoxylindoles as Novel Antimitotic and Vascular Disrupting Agents
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 4
-
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  |  
浏览/下载:3/0
  |  
提交时间:2014/12/05
Cytotoxicity and structure activity relationships of phytosterol from Phyllanthus emblica
期刊论文
FITOTERAPIA, 2013, 卷号: 84
-
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  |  
浏览/下载:4/0
  |  
提交时间:2014/12/05
Phyllanthus emblica L.
Euphorbiaceae
Phytosterol
Cytotoxicity
QSAR Studies of PTP1B Inhibitors: 1, 2-Naphthoquinone Derivatives
期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2012, 卷号: 9, 期号: 10
-
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浏览/下载:2/0
  |  
提交时间:2014/12/05
Diabetes mellitus
Multiple linear regression (MLR)
1, 2-naphoquinone derivatives
Protein tyrosine phosphatase 1B (PTP1B)
Quantitative structure-activity relationships (QSAR)
Radial basis function neural networks (RBFNN)
QSAR Studies of PTP1B Inhibitors: Recent Advances and Perspectives
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2012, 卷号: 19, 期号: 25
-
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浏览/下载:7/0
  |  
提交时间:2014/12/05
Diabetes mellitus
protein tyrosine phosphatase 1B inhibitors
type 2 diabetes
drug design
virtual screening
quantitative structure-activity relationships (QSAR)
3D-QSAR
comparative molecular field analysis (CoMFA)
comparative molecular similarity indices analysis (CoMSIA)
2D-QSAR
multiple linear regression (MLR)
radial basis function neural networks (RBFNN)
Steroidal alkaloids from Holarrhena antidysenterica as acetylcholinesterase inhibitors and the investigation for structure-activity relationships
期刊论文
LIFE SCIENCES, 2012, 卷号: 90, 期号: 23-24
-
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浏览/下载:3/0
  |  
提交时间:2014/12/05
Steroidal alkaloids
Holarrhena antidysenterica
Alzheimer's disease
Acetylcholinesterase inhibitor
Structure-activity relationships
Conessimin
Endomorphins: potential roles and therapeutic indications in the development of opioid peptide analgesic drugs
期刊论文
MEDICINAL RESEARCH REVIEWS, 2012, 卷号: 32, 期号: 3, 页码: 536-580
作者:
Liu, WX
;
Wang, R
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  |  
浏览/下载:52/0
  |  
提交时间:2015/12/22
endomorphins
analgesic drugs
structure-activity relationships
bioavailability
blood-brain barrier
Predicting the activity of drugs for a group of imidazopyridine anticoccidial compounds
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 卷号: 44, 期号: 10
-
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2014/12/05
Anticoccidial drug
Gene expression programming
cGMP-dependent protein kinase
Quantitative structure-activity relationships
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