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科研机构
山东大学 [53]
内容类型
期刊论文 [52]
会议论文 [1]
发表日期
2019 [7]
2018 [9]
2017 [9]
2016 [8]
2015 [2]
2014 [2]
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专题:山东大学
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Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3, 页码: 447-456
作者:
Wang, Zhao
;
Yu, Zhao
;
Kang, Dongwei
;
Zhang, Jian
;
Tian, Ye
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
HIV-1
NNRTIs
Doravirine
Acetamide
Prodrug
Drug design
Therapy for myocardial infarction: In vitro and in vivo evaluation of puerarin-prodrug and tanshinone co-loaded lipid nanoparticulate system
期刊论文
Biomedicine and Pharmacotherapy, 2019, 卷号: 120
作者:
Guo J.
;
Xing X.
;
Lv N.
;
Zhao J.
;
Liu Y.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Myocardial infarction
Prodrug
Puerarin
Solid lipid nanoparticles
Tanshinone
Redox-Sensitive Prodrug Molecules Meet Graphene Oxide: An Efficient Graphene Oxide-Based Nanovehicle toward Cancer Therapy
期刊论文
ACS BIOMATERIALS SCIENCE & ENGINEERING, 2019, 卷号: 5, 期号: 3, 页码: 1384-1391
作者:
Ma, Naxin
;
Song, Aixin
;
Li, Zhonghao
;
Luan, Yuxia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
graphene oxide
redox-sensitive
prodrug
cancer therapy
Enzymatic rhamnosylation of anticancer drugs by an alpha-l-rhamnosidase from Alternaria sp. L1 for cancer-targeting and enzyme-activated prodrug therapy
期刊论文
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2019, 卷号: 103, 期号: 19, 页码: 7997-8008
作者:
Xu, Li
;
Liu, Xiaohong
;
Li, Yinping
;
Yin, Zhenhao
;
Jin, Lan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Rhamnosylation
alpha-l-Rhamnosidase
Alternaria sp
L1
Cancer-targeting
Prodrug
A versatile strategy to create an active tumor-targeted chemo-photothermal therapy nanoplatform: A case of an IR-780 derivative co-assembled with camptothecin prodrug
期刊论文
ACTA BIOMATERIALIA, 2019, 卷号: 84, 页码: 356-366
作者:
He, Wenxiu
;
Jiang, Yue
;
Li, Qian
;
Zhang, Di
;
Li, Zhonghao
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
Assembly
IR-780 derivative
Camptothecin prodrug
Redox-responsive
Chemo-photothermal therapy
Preparation and evaluation of highly biocompatible nanogels with pH-sensitive charge-convertible capability based on doxorubicin prodrug
期刊论文
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2019, 卷号: 98, 页码: 161-176
作者:
Zhu, Yixin
;
Ma, Yakun
;
Zhao, Yanli
;
Yang, Min
;
Li, Lingbing
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
Doxorubicin
Polyion complex micelles
Nanogel
pH-Sensitive
Charge
conversion
Chlorambucil prodrug-participating catanionic aggregates for sustained drug release and improved antitumour activity
期刊论文
JOURNAL OF MOLECULAR LIQUIDS, 2019, 卷号: 274, 页码: 556-561
作者:
Jiang, Yue
;
Hu, Xu
;
Zhang, Jing
;
Jin, Guoxia
;
Luan, Yuxia
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Prodrug
Catanionic aggregates
Antitumour
Sustained release
Chlorambucil
Rational Design of an Amphiphilic Chlorambucil Prodrug Realizing Self-Assembled Micelles for Efficient Anticancer Therapy
期刊论文
ACS BIOMATERIALS SCIENCE & ENGINEERING, 2018, 卷号: 4, 期号: 3, 页码: 973-980
作者:
Hu, Xu
;
Liu, Ruiling
;
Zhang, Di
;
Zhang, Jing
;
Li, Zhonghao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
amphiphilic molecule
chlorambucil
prodrug
micelle
cancer therapy
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strain
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 8, 页码: 1348-1351
作者:
Huang, Boshi
;
Liu, Xinhao
;
Tian, Ye
;
Kang, Dongwei
;
Zhou, Zhongxia
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
HIV-1 NNRTI
RDEA427
Carbonate prodrug
Anti-HIV activity
Metabolic
stability
Self-assembling nanoparticles based on cytarabine prodrug for enhanced leukemia treatment
期刊论文
JOURNAL OF MOLECULAR LIQUIDS, 2018, 卷号: 251, 页码: 178-184
作者:
Liu, Ruiling
;
Zhang, Jing
;
Zhang, Di
;
Wang, Kaiming
;
Luan, Yuxia
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/11
Cytarabine
Self-assemble
Nanoparticles
Leukemia treatment
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