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科研机构
大连化学物理研究所 [31]
内容类型
期刊论文 [29]
会议论文 [2]
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2019 [1]
2018 [4]
2017 [1]
2016 [5]
2015 [4]
2014 [2]
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物理化学 [6]
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专题:大连化学物理研究所
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Short-chain chlorinated paraffins (SCCPs) disrupt hepatic fatty acid metabolism in liver of male rat via interacting with peroxisome proliferator-activated receptor a (PPAR alpha)
期刊论文
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 卷号: 181, 页码: 164-171
作者:
Gong, Yufeng
;
Zhang, Haijun
;
Geng, Ningbo
;
Ren, Xiaoqian
;
Giesy, John P.
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/12/02
SCCPs
Mode of action
PPAR alpha
Luciferase assay
Molecular docking
Metabolomics
Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2
期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 77, 页码: 320-329
作者:
Zou, Li-Wei
;
Weng, Zi-Miao
;
Ge, Guang-Bo
;
Dou, Tong-Yi
;
Wang, Ping
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/06/20
Flavonoids
Human Carboxylesterase 2 (Hce2)
Structure-inhibition Relationships
Selectivity
Inhibition Mechanism
Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2018, 卷号: 284, 页码: 48-55
作者:
Lv, Xia
;
Zhang, Jian-Bin
;
Wang, Xin-Xin
;
Hu, Wen-Zhong
;
Shi, Yu-Sheng
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/06/20
Amentoflavone
Udp-glucuronosyltransferases
Broad-spectrum Inhibitor
Herb-drug Interactions (Hdis)
A metabolomics strategy to assess the combined toxicity of polycyclic aromatic hydrocarbons (PAHs) and short-chain chlorinated paraffins (SCCPs)
期刊论文
ENVIRONMENTAL POLLUTION, 2018, 卷号: 234, 页码: 572-580
作者:
Wang, Feidi
;
Zhang, Haijun
;
Geng, Ningbo
;
Ren, Xiaoqian
;
Zhang, Baoqin
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/06/20
Combined Toxicity
Metabolomics
Polycyclic Aromatic Hydrocarbons
Short-chain Chlorinated Paraffins
Assessment of hepatic metabolism-dependent nephrotoxicity on an organs-on-a-chip microdevice
期刊论文
TOXICOLOGY IN VITRO, 2018, 卷号: 46, 页码: 1-8
作者:
Li, Zhongyu
;
Jiang, Lei
;
Zhu, Yujuan
;
Su, Wentao
;
Xu, Cong
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/06/20
Microfluidics
Drug Testing
Hepatic Metabolism
Nephrotoxicity
Organs-on-a-chip
Structure-activity relationships of flavonoids as natural inhibitors against E. coli beta-glucuronidase
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2017, 卷号: 109, 页码: 975-983
作者:
Wu, Da-Chang
;
Zou, Li-Wei
;
Dou, Tong-Yi
;
Yang, Ling
;
Zhang, Tong-Yan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/06/20
Flavonoids
E. Coli bE.a-glucuronidasE.
Structure-inhibition Relationships
Scutellarein
Luteolin
A novel cell cycle blocker extracted from Stellera chamaejasme L. inhibits the proliferation of hepatocarcinoma cells
期刊论文
ONCOLOGY REPORTS, 2016, 卷号: 35, 期号: 6, 页码: 3480-3488
作者:
Kan, Xiao-Xi
;
Li, Qi
;
Chen, Xi
;
Wang, Ya-Jie
;
Li, Yu-Jie
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/06/20
Cell Cycle Arrest
Hepatocarcinoma
Cyclin B1
Cdk1 SteL.era Chamaejasme L.
Modulation of Carbon Nanotubes' Perturbation to the Metabolic Activity of CYP3A4 in the Liver
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2016, 卷号: 26, 期号: 6, 页码: 841-850
作者:
Wang, Wenyi
;
Zhu, Hao
;
Yan, Bing
;
Zhang, Yi
;
Wang, Yabin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/06/20
Combinatorial Chemistry
Cyp450
Functionalized Mwcnts
Human Liver Microsome
Pharmacophores
Irinotecan (CPT-11)-induced elevation of bile acids potentiates suppression of IL-10 expression
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2016, 卷号: 291, 页码: 21-27
作者:
Fang, Zhong-Ze
;
Zhang, Dunfang
;
Cao, Yun-Feng
;
Xie, Cen
;
Lu, Dan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/06/20
Irinotecan (Cpt-11)
Metabolomics
Bile Acids
Interleukin-10
Assessment of metabolism-dependent drug efficacy and toxicity on a multilayer organs-on-a-chip
期刊论文
INTEGRATIVE BIOLOGY, 2016, 卷号: 8, 期号: 10, 页码: 1022-1029
作者:
Qin, Jianhua
;
Li, Zhongyu
;
Guo, Yaqiong
;
Yu, Yue
;
Xu, Cong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/06/20
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