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科研机构
上海药物研究所 [397]
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期刊论文 [395]
会议论文 [2]
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2021 [47]
2020 [46]
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A camptothecin-based, albumin-binding prodrug enhances efficacy and safety in vivo
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 226, 页码: 11
作者:
Cheng, Zhiyang
;
Huang, Ying
;
Shen, Qianqian
;
Zhao, Yangrong
;
Wang, Lei
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/11/04
Cancer
beta-glucuronidase
Bioconjugation
Albumin
Camptothecin
Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
Metal-organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics
期刊论文
CHEMICAL COMMUNICATIONS, 2021, 卷号: 57, 期号: 91, 页码: 12098-12110
作者:
Tong, Pei-Hong
;
Zhu, Ling
;
Zang, Yi
;
Li, Jia
;
He, Xiao-Peng
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/12/16
Nanomedicine Strategies to Circumvent Intratumor Extracellular Matrix Barriers for Cancer Therapy
期刊论文
ADVANCED HEALTHCARE MATERIALS, 2021, 页码: 25
作者:
Xu, Xiaoxuan
;
Wu, Yao
;
Qian, Xindi
;
Wang, Yuqi
;
Wang, Jiaoying
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/12/16
cancer therapy
drug delivery
extracellular matrix
nanomedicine
tumor penetration
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:
Huang, Ying
;
Wang, Lei
;
Cheng, Zhiyang
;
Yang, Biyu
;
Yu, Jiahui
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Antitumour
Chemotherapy
SN38
Drug delivery systems
Albumin
Combating liver cancer through GO-targeted biomaterials
期刊论文
BIOMEDICAL MATERIALS, 2021, 卷号: 16, 期号: 6, 页码: 14
作者:
Huang, Xing
;
Zhang, Jiaxin
;
Song, Yijie
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/11/04
graphene oxide
hydroxycamptothecin
anti-cancer
drug delivery system
targeting
Transfersomes improved delivery of ascorbic palmitate into the viable epidermis for enhanced treatment of melasma
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 608, 页码: 10
作者:
Li, Junjun
;
Duan, Nianxiu
;
Song, Sha
;
Nie, Di
;
Yu, Miaorong
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  |  
浏览/下载:69/0
  |  
提交时间:2021/11/04
Transfersome
Drug delivery
Ascorbic palmitate
Viable epidermis
Melasma treatment
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
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  |  
浏览/下载:43/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
A five-dimensional data collection strategy for multicomponent discovery and characterization in Traditional Chinese Medicine: Gastrodia Rhizoma as a case study
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2021, 卷号: 1653, 页码: 12
作者:
Zhu, Haodong
;
Wu, Xingdong
;
Huo, Jiangyan
;
Hou, Jinjun
;
Long, Huali
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2021/11/04
Gastrodia Rhizoma
Multidimensional data acquisition
Offline 2D-LC-IMS-DIA MS
MS
Neutral loss (NLs)
Collision cross section (CCS)
Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 9, 页码: 19
作者:
Xiong, Zhaoping
;
Jeon, Minji
;
Allaway, Robert J.
;
Kang, Jaewoo
;
Park, Donghyeon
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/11/04
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