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CORC

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An overview of kinase downregulators and recent advances in discovery approaches 期刊论文
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6
作者:  Wang, Beilei;  Wu, Hong;  Hu, Chen;  Wang, Haizhen;  Liu, Jing
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/25
Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:  Xue, Haitao;  Guo, Shuang;  Hu, Tianwen;  Wei, Daibao;  Xie, Yuanchao
收藏  |  浏览/下载：38/0  |  提交时间：2022/01/18
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:  Yang, Xiangbo;  Lu, Huimin;  Xie, Hang;  Zhang, Binbin;  Nie, Tianqing
收藏  |  浏览/下载：24/0  |  提交时间：2022/01/18
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang
收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18
Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12050202] 项目
项目编号: XDA12050202, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
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收藏  |  浏览/下载：164/0  |  提交时间：2021/05/24
Accucopy: accurate and fast inference of allele-specific copy number alterations from low-coverage low-purity tumor sequencing data 期刊论文
BMC BIOINFORMATICS, 2021, 卷号: 22, 期号: 1, 页码: 18
作者:  Fan, Xinping;  Luo, Guanghao;  Huang, Yu S.
收藏  |  浏览/下载：214/0  |  提交时间：2021/05/24
Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12020229] 项目
项目编号: XDA12020229, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development, Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
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收藏  |  浏览/下载：2/0  |  提交时间：2022/01/18
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei
收藏  |  浏览/下载：45/0  |  提交时间：2022/01/18
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  Fu, Weitao;  Zhang, Minkui;  Liao, Jianing;  Tang, Qing;  Lei, Yixuan
收藏  |  浏览/下载：53/0  |  提交时间：2022/03/21
Picture-word order compound protein interaction: Predicting compound-protein interaction using structural images of compounds 期刊论文
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2021, 页码: 10
作者:  Qian, Ying;  Li, Xuelian;  Wu, Jian;  Zhou, Aimin;  Xu, Zhijian
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04

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