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CORC

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Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:  Lu, Dasheng;  Liu, Yameng;  Luo, Yuhong;  Zhao, Jie;  Feng, Chao
收藏  |  浏览/下载：46/0  |  提交时间：2022/01/18
The Novel Chinese Medicine JY5 Formula Alleviates Hepatic Fibrosis by Inhibiting the Notch Signaling Pathway 期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 15
作者:  Fu, Yadong;  Xiao, Zhun;  Tian, Xiaoting;  Liu, Wei;  Xu, Zhou
收藏  |  浏览/下载：27/0  |  提交时间：2022/01/04
Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199
作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan
收藏  |  浏览/下载：40/0  |  提交时间：2021/11/04
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:  Tang, Xuehang;  Ning, Mengmeng;  Ye, Yangliang;  Gu, Yipei;  Yan, Hongyi
收藏  |  浏览/下载：49/0  |  提交时间：2021/11/04
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:  Lan, Xiao-fang;  Olaleye, Olajide E.;  Lu, Jun-lan;  Yang, Wei;  Du, Fei-fei
收藏  |  浏览/下载：71/0  |  提交时间：2021/06/11
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity 期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:  Qiao, Shida;  Feng, Sisi;  Wu, Zhitao;  He, Ting;  Ma, Chen
收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24
Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism 期刊论文
NATURE METABOLISM, 2021, 页码: 31
作者:  Xu, Yanyong;  Li, Yuanyuan;  Jadhav, Kavita;  Pan, Xiaoli;  Zhu, Yingdong
收藏  |  浏览/下载：32/0  |  提交时间：2021/05/24
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:  Li, Junyou;  Liu, Mengqi;  Li, Yazhou;  Sun, Dan-dan;  Shu, Zhihao
收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:  Wang, Ying;  Zhu, Yao;  Niu, Junxing;  Deng, Qiangqiang;  Guo, Shimeng
收藏  |  浏览/下载：59/0  |  提交时间：2020/12/21
Design of G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) soft drugs with reduced gallbladder-filling effects 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 12
作者:  Han, Fanghui;  Ning, Mengmeng;  Cao, Hua;  Ye, Yangliang;  Feng, Ying
收藏  |  浏览/下载：32/0  |  提交时间：2020/12/21

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