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科研机构
上海药物研究所 [21]
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期刊论文 [21]
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2021 [1]
2018 [5]
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Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:
Lan, Xiao-fang
;
Olaleye, Olajide E.
;
Lu, Jun-lan
;
Yang, Wei
;
Du, Fei-fei
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/06/11
LianhuaQingwen
glycyrrhetic acid
24-hydroxyglycyrrhetic acid
Gancao-induced pseudoaldosteronism
licorice-induced pseudoaldosteronism
11β
-hydroxysteroid dehydrogenase 2
COVID-19
colonic microbiota
Baicalin relaxes vascular smooth muscle and lowers blood pressure in spontaneously hypertensive rats
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 111, 页码: 325-330
作者:
Ding, Liliqiang
;
Jia, Chenglin
;
Zhang, Yong
;
Wang, Wenjian
;
Zhu, Weiliang
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
Glycyrrhizin has a high likelihood to be a victim of drug-drug interactions mediated by hepatic organic anion-transporting polypeptide 1B1/1B3
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 17, 页码: 3486-3503
作者:
Dong, Jiajia
;
Olaleye, Olajide E.
;
Jiang, Rongrong
;
Li, Jing
;
Lu, Chuang
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2019/01/08
Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 212-242
作者:
Dal Maso, Emma
;
Zhu, Yue
;
Vi Pham
;
Reynolds, Christopher A.
;
Deganutti, Giuseppe
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
G protein-coupled receptor
Calcitonin receptor
GPCR structure-function
Biased agonism
Molecular modelling
Facilitating Anti-Cancer Combinatorial Drug Discovery by Targeting Epistatic Disease Genes
期刊论文
Molecules (Basel, Switzerland), 2018, 卷号: 23, 期号: 4
作者:
Quan, Yuan
;
Liu, Meng-Yuan
;
Liu, Ye-Mao
;
Zhu, Li-Da
;
Wu, Yu-Shan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
The dual-inhibitory effect of miR-338-5p on the multidrug resistance and cell growth of hepatocellular carcinoma
期刊论文
Signal transduction and targeted therapy, 2018, 卷号: 3, 页码: 3
作者:
Zhao, Yang
;
Chen, Jing
;
Wei, Wenxin
;
Qi, Xinming
;
Li, Chunzhu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Remote Loading of Small-Molecule Therapeutics into Cholesterol-Enriched Cell-Membrane-Derived Vesicles
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 卷号: 56, 期号: 45, 页码: 14075-14079
作者:
Zhang, Xinxin
;
Angsantikul, Pavimol
;
Ying, Man
;
Zhuang, Jia
;
Zhang, Qiangzhe
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
biocompatibility
biomimetic nanotechnology
cell membrane
drug delivery
remote loading
Sulfated fucoidan FP08S2 inhibits lung cancer cell growth in vivo by disrupting angiogenesis via targeting VEGFR2/VEGF and blocking VEGFR2/Erk/VEGF signaling
期刊论文
CANCER LETTERS, 2016, 卷号: 382, 期号: 1, 页码: 44-52
作者:
Chen, Huanjun
;
Cong, Qifei
;
Du, Zhenyun
;
Liao, Wenfeng
;
Zhang, Lei
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Fucoidan
Angiogenesis
VEGF
Lung cancer
A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 8, 页码: 9430-9448
作者:
Fu, Zhi-guang
;
Wang, Li
;
Cui, Hong-yong
;
Peng, Jian-long
;
Wang, Shi-jie
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
CD147
small molecule inhibitor
hepatocellular carcinoma cells
metastasis
dimerization
KCNQ potassium channels in sensory system and neural circuits
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 1, 页码: 25-33
作者:
Wang, Jing-jing
;
Li, Yang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
KCNQ channels
M channels
neural circuits
channelopathy
epilepsy
neuropathic pain
deafness
mental illness
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