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山东大学 [33]
武汉大学 [21]
复旦大学上海医学院 [16]
上海中医药大学 [14]
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期刊论文 [154]
会议论文 [3]
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2019 [157]
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3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:
Shan, Hui
;
Yao, Sheng
;
Ye, Yang
;
Yu, Qiang
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
JAK/STAT
3-deoxy-2 beta,16-dihydroxynagilactone E
tyrosine kinase inhibitor
allosteric inhibitor
cancer
H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 520, 期号: 1, 页码: 93-98
作者:
Li, Fengli
;
Wang, Jing
;
Wu, Ning
;
Zhang, Hua
;
Li, Zheng
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/03/20
5-FU
Drug resistance
STAT3
Hepatocellular carcinoma
MCL-1
PUMA
SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC
期刊论文
AUTOPHAGY, 2019, 页码: 15
作者:
Zhang, Sulin
;
Yang, Zhiwen
;
Bao, Weilian
;
Liu, Lixin
;
You, Yan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2020/07/01
Colorectal cancer
macroautophagy
SNX10
SRC
tumor growth
Xanthatin inhibits STAT3 and NF-kappa B signalling by covalently binding to JAK and IKK kinases
期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 6, 页码: 4301-4312
作者:
Liu, Man
;
Xiao, Cheng-qian
;
Sun, Ming-wei
;
Tan, Min-jia
;
Hu, Li-hong
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/07/01
covalent interaction
IKK inhibitor
JAK inhibitor
natural compound
The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 13
作者:
Zhang, Ning
;
Han, Li
;
Xue, Yaru
;
Deng, Qiangqiang
;
Wu, Zhitao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
magnesium lithospermate B
hepatic ischemia/reperfusion
acute injury
anti-inflammation
Jak2/Stat3 signaling pathway
Synthetic derivatives of the natural product 13-amino 2-desoxy-4-epi-pulchellin inhibit STAT3 signaling and induce G2/M arrest and death of colon cancer cells
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 782-785
作者:
Niu, Junxing
;
Huang, Hui
;
Wang, Fei
;
Zhang, Xianjing
;
Liu, Yi
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Sesquiterpene-lactone
JAK2/STAT3
Michael addition reaction
Antitumor
Colorectal carcinoma
Cell Permeable NBD Peptide-Modified Liposomes by Hyaluronic Acid Coating for the Synergistic Targeted Therapy of Metastatic Inflammatory Breast Cancer
期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 3, 页码: 1140-1155
作者:
Sun, Yuqing
;
Li, Xuqian
;
Zhang, Lili
;
Liu, Xiao
;
Jiang, Baohong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
TAT-NBD peptide
curcumin
celecoxib
anti-inflammation
antimetastasis
2-ethoxystypandrone, a novel small-molecule stat3 signaling inhibitor from polygonum cuspidatum, inhibits cell growth and induces apoptosis of hcc cells and hcc cancer stem cells
期刊论文
Bmc complementary and alternative medicine, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2019/05/08
Polygonum cuspidatum
2-ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
Stat3 signaling pathway
Cancer stemness inhibitor
2-Ethoxystypandrone, a novel small-molecule STAT3 signaling inhibitor from Polygonum cuspidatum, inhibits cell growth and induces apoptosis of HCC cells and HCC Cancer stem cells
期刊论文
BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 卷号: 19, 页码: 13
作者:
Li, Wuguo
;
Zhang, Qing
;
Chen, Kaotan
;
Sima, Zhenhua
;
Liu, Jingli
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/07/01
Polygonum cuspidatum
2-Ethoxystypandrone
Hepatocellular carcinoma
Cancer stem cells
STAT3 signaling pathway
Cancer stemness inhibitor
Gastrodin Inhibits Inflammasome Through the STAT3 Signal Pathways in TNA2 Astrocytes and Reactive Astrocytes in Experimentally Induced Cerebral Ischemia in Rats
期刊论文
NEUROMOLECULAR MEDICINE, 2019, 卷号: 21, 期号: 3
作者:
Sui, Yue
;
Bian, Ligong
;
Ai, Qinglong
;
Yao, Yueyi
;
Yu, Mali
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2019/12/04
Gastrodin
OGD-astrocytes
Anti-inflammatory
NLRP3
NLRC4
STAT3 signaling
Cerebral ischemia
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