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科研机构
上海药物研究所 [941]
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期刊论文 [933]
会议论文 [7]
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2021 [58]
2020 [65]
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Biochemis... [18]
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Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17
作者:
Li, Xinzhi
;
Yuan, Bingchuan
;
Lu, Min
;
Wang, Yuqin
;
Ding, Na
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/01/18
Picture-word order compound protein interaction: Predicting compound-protein interaction using structural images of compounds
期刊论文
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2021, 页码: 10
作者:
Qian, Ying
;
Li, Xuelian
;
Wu, Jian
;
Zhou, Aimin
;
Xu, Zhijian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/04
compound-protein interaction
convolutional neural network (CNN)
drug-drug interaction
image processing
structural images
Metal-organic frameworks (MOFs) as host materials for the enhanced delivery of biomacromolecular therapeutics
期刊论文
CHEMICAL COMMUNICATIONS, 2021, 卷号: 57, 期号: 91, 页码: 12098-12110
作者:
Tong, Pei-Hong
;
Zhu, Ling
;
Zang, Yi
;
Li, Jia
;
He, Xiao-Peng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/16
Discrete genetic loci in human gutBacteroides thetaiotaomicron confer pectin metabolism
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 272, 页码: 13
作者:
Li, Meixia
;
Li, Saijuan
;
Guo, Xiaozhen
;
Guo, Ciliang
;
Wang, Yeqin
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/11/04
Polysaccharide
Pectin
Human gut microbiota
Metabolism
Bacteroides
Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:
Fan, Shijie
;
Yue, Liyan
;
Wan, Wei
;
Zhang, Yuanyuan
;
Zhang, Bidong
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/12/16
covalent modification
probes
proteome
LC3
post-translational modification
Quantitative proteomic analysis uncovers inhibition of melanin synthesis by silk fibroin via MITF/tyrosinase axis in B16 melanoma cells
期刊论文
LIFE SCIENCES, 2021, 卷号: 284, 页码: 7
作者:
Wang, Yuqiu
;
Duan, Tianbi
;
Hong, Minhua
;
Zhou, Yanting
;
Huang, Hui
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/11/04
Silk fibroin
Quantitative proteomics
Melanin
Microphthalmia-associated transcription factor
Tyrosinase
Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella
期刊论文
RSC MEDICINAL CHEMISTRY, 2021, 页码: 12
作者:
Guan, Xiang-Na
;
Zhang, Tao
;
Yang, Teng
;
Dong, Ze
;
Yang, Song
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/12/16
A simultaneous identification and quantification strategy for determination of sulfhydryl-containing metabolites in normal- and high-fat diet hamsters using stable isotope labeling combined with LC-MS
期刊论文
ANALYTICA CHIMICA ACTA, 2021, 卷号: 1184, 页码: 13
作者:
Chang, Lu
;
Lin, Feifei
;
Cheng, Kai
;
Li, Jiaomeng
;
Sun, Xiaochu
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/01/18
Sulfhydryl-containing metabolites
Stable isotope labeling
Identification
Quantification
Hyperlipidemia
Oxidative stress
The potent radioprotective agents: Novel nitronyl nitroxide radical spin-labeled resveratrol derivatives
期刊论文
FITOTERAPIA, 2021, 卷号: 155, 页码: 7
作者:
Luo, Guoying
;
Sun, Lanlan
;
Li, Heng
;
Chen, Jia
;
He, Peilan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/01
Ionizing radiation
Resveratrol
Nitronyl nitroxide radical
Radioprotection effects
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