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上海药物研究所 [4]
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期刊论文 [11]
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2020 [11]
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Biology [1]
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The Role of alpha-Synuclein Oligomers in Parkinson's Disease
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 22, 页码: 17
作者:
Du, Xiao-yu
;
Xie, Xi-xiu
;
Liu, Rui-tian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/03/29
α
-synuclein
Parkinson’
s disease
oligomers
structure
toxicity
Ultra-High-Resolutionin vitroMRI Study of Age-Related Brain Subcortical Susceptibility Alteration in Rhesus Monkeys at 9.4 T
期刊论文
FRONTIERS IN AGING NEUROSCIENCE, 2020, 卷号: 12
作者:
Wen, Qingqing
;
Yang, Hongyi
;
Li, Jiali
;
Zhang, Jin
;
Tong, Haiyang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/10/26
quantitative susceptibility mapping
iron concentration
brain aging
rhesus monkey
high resolution
9
4 T
Intrinsic connectivity identifies the sensory-motor network as a main cross-network between remitted late-life depression- and amnestic mild cognitive impairment-targeted networks
期刊论文
BRAIN IMAGING AND BEHAVIOR, 2020, 卷号: 14, 期号: 4, 页码: 1130-1142
作者:
Chen, Jiu
;
Shu, Hao
;
Wang, Zan
;
Zhan, Yafeng
;
Liu, Duan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/08/24
Remitted late-life depression
Amnestic mild cognitive impairment
Functional connectivity
Sensory-motor network
Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5
期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18
作者:
Han, Haozhen
;
Li, Chunpu
;
Li, Man
;
Yang, Lisheng
;
Zhao, Sen
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/24
sirtuins
inhibitor
structure-activity relationship
deacetylase
An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tao, Ling-xue
;
Ji, Sha-sha
;
Szaloki, Dora
;
Kovacs, Tibor
;
Mandi, Attila
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
neurodegeneration
oxidative stress
apoptosis
MAPK pathway
PI3K
Akt pathway
SH-SY5Y neuroblastoma cells
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:
Xu Mingming
;
Ryan Philip
;
Rudrawar Santosh
;
Quinn Ronald J
;
Zhang Haiyan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Parkinson’s disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death
期刊论文
AUTOPHAGY, 2020, 卷号: 16, 期号: 3, 页码: 531-547
作者:
Wan, Huida
;
Wang, Qi
;
Chen, Xiuting
;
Zeng, Qiufang
;
Shao, Yanjiao
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/11/10
ER stress
neuronal apoptosis
quantitative proteomics
UPR
WDR45
2,3,7,8-Tetrachlorodibenzo-p-dioxin and up-regulation of neurofilament expression in neuronal cells: Evaluation of AhR and MAPK pathways
期刊论文
ENVIRONMENT INTERNATIONAL, 2020, 卷号: 134, 页码: 1-15
作者:
Chen, Yangsheng
;
Xie, Heidi Qunhui
;
Sha, Rui
;
Xu, Tuan
;
Zhang, Songyan
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/09/14
Apoptotic neurodegeneration in whitefly promotes the spread of TYLCV
期刊论文
ELIFE, 2020, 卷号: 9
作者:
Wang Shifan
;
Guo HJ(郭慧娟)
;
Ge F(戈峰)
;
Sun YC(孙玉诚)
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2021/10/26
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