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上海药物研究所 [35]
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期刊论文 [103]
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2020 [105]
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A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:
Wang, Zhen
;
Zhang, Hao
;
Chen, Baoen
;
Ouyang, Sisheng
;
Zheng, Tong
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2021/05/24
SPOP
Protein‐
protein interaction
Clear cell Renal Cell Carcinomas
Crystal structure
Peptide inhibitor
Genetic Diversity, Inbreeding Level, and Genetic Load in Endangered Snub-Nosed Monkeys (Rhinopithecus)
期刊论文
FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 10
作者:
Kuang, Weimin
;
Hu, Jingyang
;
Wu, Hong
;
Fen, Xiaotian
;
Dai, Qingyan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/09/17
snub-nosed monkeys
population genomics
genetic diversity
inbreeding
genetic load
population decline
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Deep learning algorithm to improve hypertrophic cardiomyopathy mutation prediction using cardiac cine images
期刊论文
EUROPEAN RADIOLOGY, 2020, 页码: 10
作者:
Zhou, Hongyu
;
Li, Lu
;
Liu, Zhenyu
;
Zhao, Kankan
;
Chen, Xiuyu
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/01/06
Cardiomyopathy
hypertrophic
Genotype
Deep learning
Magnetic resonance imaging
Immune microenvironment features and efficacy of PD-1/PD-L1 blockade in non-small cell lung cancer patients with EGFR or HER2 exon 20 insertions
期刊论文
THORACIC CANCER, 2020
作者:
Chen, Kaiyan
;
Pan, Guoqiang
;
Cheng, Guoping
;
Zhang, Fanrong
;
Xu, Yanjun
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/28
EGFR
HER2
immunotherapy
NSCLC
PD‐
L1
Investigation of precipitation concentration and trends and their potential drivers in the major river basins of Central Asia
期刊论文
ATMOSPHERIC RESEARCH, 2020, 卷号: 245, 页码: 18
作者:
Yang, Peng
;
Zhang, Yongyong
;
Xia, Jun
;
Sun, Shangxin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2021/03/16
Climate Change
Precipitation Concentration
Teleconnection Indices
Central Asia
Abrupt Change
Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase
期刊论文
ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003
作者:
Butler, Joshua H.
;
Baptista, Rodrigo P.
;
Valenciano, Ana L.
;
Zhou, Bin
;
Kissinger, Jessica C.
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
Plasmodium
PfPARE
structure-resistance relationship study
Malaria Box
Pathogen Box
lindenane sesquiterpenoid dimers
Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:
Wang, Yuwei
;
Tang, Shuai
;
Lai, Huanling
;
Jin, Ruyi
;
Long, Xu
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/12/24
IDH1
gliomas
molecular docking
virtual screening
docking-based virtual screening
Morphology and phylogenetic analysis of five deep-sea golden gorgonians (Cnidaria, Octocorallia, Chrysogorgiidae) in the Western Pacific Ocean, with the description of a new species
期刊论文
ZOOKEYS, 2020, 期号: 989, 页码: 1-37
作者:
Xu, Yu
;
Zhan, Zifeng
;
Xu, Kuidong
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/04/12
Anthozoa br
Chrysogorgia dendritica br
Chrysogorgia carolinensis br
Metallogorgia br
Pseudochrysogorgia br
seamount br
Modes of genetic adaptations underlying functional innovations in the rumen
期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2020, 页码: 21
作者:
Pan, Xiangyu
;
Cai, Yudong
;
Li, Zongjun
;
Chen, Xianqing
;
Heller, Rasmus
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2021/01/14
rumen innovations
comparative transcriptomics
comparative genomics
evo-devo
evolution of organs
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