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YES1amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer 期刊论文
BRITISH JOURNAL OF CANCER, 2020, 页码: 12
作者:  Wang, Lei;  Wang, Quanren;  Xu, Piaopiao;  Fu, Li;  Li, Yun
收藏  |  浏览/下载:15/0  |  提交时间:2020/12/24
metabolismanddispositionofpyrotinibinhealthymalevolunteerscovalentbindingwithhumanplasmaprotein 期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 7, 页码: 980
作者:  Meng Jian;  Liu Xiaoyun;  Ma Sheng;  Zhang Hua;  Yu Songda
收藏  |  浏览/下载:1/0  |  提交时间:2020/07/01
Metabolism and disposition of pyrotinib in healthy male volunteers: covalent binding with human plasma protein 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Meng, Jian;  Liu, Xiao-Yun;  Ma, Sheng;  Zhang, Hua;  Yu, Song-da
收藏  |  浏览/下载:98/0  |  提交时间:2019/01/08
STAT3 activation confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive breast cancer 期刊论文
CANCER SCIENCE, 2018, 卷号: 109, 期号: 10, 页码: 3305-3315
作者:  Wang, Lei;  Wang, Quanren;  Gao, Mingzhao;  Fu, Li;  Li, Yun
收藏  |  浏览/下载:50/0  |  提交时间:2019/01/08
Synergistic effect of a novel autophagy inhibitor and Quizartinib enhances cancer cell death 期刊论文
CELL DEATH & DISEASE, 2018, 卷号: 9
作者:  Ouchida, Amanda Tomie;  Li, Yingbo;  Geng, Jiefei;  Najafov, Ayaz;  Ofengeim, Dimitry
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3K alpha-selective inhibitor CYH33 in breast cancer 期刊论文
CANCER LETTERS, 2018, 卷号: 433, 页码: 273-282
作者:  Liu, Xue-ling;  Xu, Yi-chao;  Wang, Yu-xiang;  Chen, Yi;  Wang, Bo-bo
收藏  |  浏览/下载:42/0  |  提交时间:2019/01/08
Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:  Li, Xin;  Yang, Changyong;  Wan, Hong;  Zhang, Ge;  Feng, Jun
收藏  |  浏览/下载:136/0  |  提交时间:2019/01/08
Aberrant intracellular metabolism of T-DM1 confers T-DM1 resistance in human epidermal growth factor receptor 2-positive gastric cancer cells 期刊论文
CANCER SCIENCE, 2017, 卷号: 108, 期号: 7, 页码: 1458-1468
作者:  Wang, Hongbin;  Wang, Wenqian;  Xu, Yongping;  Yang, Yong;  Chen, Xiaoyan
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08
Integration of Receptor Tyrosine Kinases Determines Sensitivity to PI3K alpha-selective Inhibitors in Breast Cancer 期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 4, 页码: 974-986
作者:  Xu, Yi-chao;  Wang, Xiang;  Chen, Yi;  Chen, Si-meng;  Yang, Xin-ying
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry 期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 117-127
作者:  Zhu, Yunting;  Li, Liang;  Zhang, Ge;  Wan, Hong;  Yang, Changyong
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08


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