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中国医学科学院 北... [10]
暨南大学 [7]
上海中医药大学 [6]
上海药物研究所 [4]
武汉大学 [4]
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期刊论文 [60]
会议论文 [1]
发表日期
2017 [61]
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Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:
Zhou, Shengbin
;
Duan, Yanan
;
Wang, Jiang
;
Zhang, Jin
;
Sun, Haifeng
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Tetrahydroberberine
4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines
Mitochondrial respiration
AMPK indirect activators
db/db mice
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:
Yang, Na
;
Sun, Run-Bin
;
Chen, Xing-Long
;
Zhen, Le
;
Ge, Chun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2017/05/19
hyperglycemia
glucose-lowering effect
berberine
berberrubine
glucuronide
alpha-glycosidase
HFD-induced hyperglycemia model of C57BL/6 mice
human normal liver cell line L-O2
pharmacokinetics
The synthesis and antistaphylococcal activity of 9, 13-disubstituted berberine derivatives
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 127, 页码: 424-433
作者:
Wang, Jing
;
Yang, Teng
;
Chen, Huang
;
Xu, Yun-Nan
;
Yu, Li-Fang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Berberine derivatives
Antistaphylococcal activity
Multidrug-resistant
Cytotoxicity
Advances in the study of berberine and its derivatives: a focus on anti-inflammatory and anti-tumor effects in the digestive system
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 2, 页码: 157-167
作者:
Zou, Kun
;
Li, Zhao
;
Zhang, Yong
;
Zhang, Hao-yue
;
Li, Bo
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
berberine
natural product
anti-inflammatory drug
anticancer drug
digestive system
structure-activity relationship
Berberine-induced bioactive metabolites of the gut microbiota improve energy metabolism
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2017, 卷号: 70
作者:
Wang, Yan
;
Shou, Jia-Wen
;
Li, Xiao-Yang
;
Zhao, Zhen-Xiong
;
Fu, Jie
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Berberine
Gut microbiota
Butyrate
Blood lipids and glucose
Gut Microbiota-Mediated Personalized Treatment of Hyperlipidemia Using Berberine
期刊论文
THERANOSTICS, 2017, 卷号: 7, 期号: 9
作者:
He, Chi-Yu
;
Zhao, Zhen-Xiong
;
Shou, Jia-Wen
;
Tong, Qian
;
Wang, Yan
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Berberine
Hyperlipidemia
Gut microbiota
Nitroreductase
Absorption
Bioavailability
Berberine enhances the AMPK activation and autophagy and mitigates high glucose-induced apoptosis of mouse podocytes
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2017, 卷号: 794
作者:
Chen, Li
;
Jin, Yingli
;
Liu, Shuping
;
Ma, Qingshan
;
Xiao, Dong
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Berberine
High glucose
AMPK
Autophagy
Podocyte
Involvement of P-glycoprotein and multidrug and toxin extrusion protein 1 in hepatic and renal berberine efflux in mice
期刊论文
RSC ADVANCES, 2017, 卷号: 7, 期号: 55
作者:
Wang, Guofeng
;
Jin, Jingyi
;
Zeng, Jiakai
;
Shi, Rong
;
Dai, Yan
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
Polyethylene glycol 400 (PEG400) affects the systemic exposure of oral drugs based on multiple mechanisms: taking berberine as an example
期刊论文
RSC ADVANCES, 2017, 卷号: 7, 期号: 5
作者:
Ma, Bing-Liang
;
Yang, Yan
;
Dai, Yan
;
Li, Qiao
;
Lin, Ge
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Berberine alleviates dextran sodium sulfate-induced colitis by improving intestinal barrier function and reducing inflammation and oxidative stress
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 卷号: 13, 期号: 6
作者:
Zhang, Li-Chao
;
Wang, Yue
;
Tong, Ling-Chang
;
Sun, Sheng
;
Liu, Wei-Ye
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
ulcerative colitis
berberine
intestinal barrier function
tight junction protein
dextran sulfate sodium
inflammation
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