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科研机构
山东大学 [147]
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期刊论文 [146]
会议论文 [1]
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2019 [13]
2018 [13]
2017 [12]
2016 [19]
2015 [22]
2014 [8]
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Design, synthesis, and biological evaluation of 2-(5-methyl-1H-pyrazol-1-yl) acetamide derivatives as androgen receptor antagonists
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 3, 页码: 380-386
作者:
Dong, Junze
;
Zhang, Jingya
;
Li, Zilu
;
Asnake, Solomon
;
Zhang, Daoguang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Androgen receptor
Prostate cancer
Antagonists
Pyrazole derivatives
Molecular docking and biological evaluation of novel urea-tailed mannich base against Pseudomonas aeruginosa
期刊论文
MICROBIAL PATHOGENESIS, 2019, 卷号: 130, 页码: 104-111
作者:
Mohanvel, Sucharitha Kannappan
;
Ravichandran, Vinothkannan
;
Kamalanathan, Chakkaravarthi
;
Satish, Arm Susan
;
Ramesh, Samiraj
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
Quorum sensing
LasR
Quorum sensing inhibition
Biofilms
Mannich base
Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3, 页码: 447-456
作者:
Wang, Zhao
;
Yu, Zhao
;
Kang, Dongwei
;
Zhang, Jian
;
Tian, Ye
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
HIV-1
NNRTIs
Doravirine
Acetamide
Prodrug
Drug design
Design, synthesis and biological evaluation of "Multi-Site"-binding influenza virus neuraminidase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178, 页码: 64-80
作者:
Jia, Ruifang
;
Zhang, Jian
;
Ai, Wei
;
Ding, Xiao
;
Desta, Samuel
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/11
Influenza virus
Neuraminidase inhibitors
430-Cavity
150-Cavity
Oseltamivir derivatives
Design, Synthesis, and Biological Evaluation of 2,4-Imidazolinedione Derivatives as HDAC6 Isoform-Selective Inhibitors
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 8, 页码: 1122-1127
作者:
Liang, Tao
;
Hou, Xuben
;
Zhou, Yi
;
Yang, Xinying
;
Fang, Hao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
HDAC6
isoform-selective
2,4-imidazolinedione
antiproliferative
apoptosis
Preparation and evaluation of highly biocompatible nanogels with pH-sensitive charge-convertible capability based on doxorubicin prodrug
期刊论文
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2019, 卷号: 98, 页码: 161-176
作者:
Zhu, Yixin
;
Ma, Yakun
;
Zhao, Yanli
;
Yang, Min
;
Li, Lingbing
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
Doxorubicin
Polyion complex micelles
Nanogel
pH-Sensitive
Charge
conversion
Design, synthesis and biological evaluation of novel 2,3-indolinedione derivatives against mantle cell lymphoma
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3319-3327
作者:
Yu, Shengping
;
Liu, Yang
;
Zhang, Zhen
;
Zhang, Jingya
;
Zhao, Guisen
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/11
2,3-Indolinedione
Mantle cell lymphoma
Derivatives
Biological
activities
Synthesis and biological activities evaluation of sanjuanolide and its analogues
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 326-328
作者:
Zhai, Jiadai
;
Fu, Lin
;
Li, Yuanyuan
;
Zhao, Rui
;
Wang, Rui
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Isoprenylated chalcone
Hydroxyisoprenyl group
Natural product
Analogues
Biological activity
Design, synthesis, and biological evaluation of novel nitrogen heterocycle-containing ursolic acid analogs as antitumor agents
期刊论文
Molecules, 2019
作者:
Wang W.
;
Lei L.
;
Liu Z.
;
Wang H.
;
Meng Q.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
Antitumor activity
Apoptosis
Nitrogen heterocycles
Synthesis
Ursolic acid analogues
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
作者:
Wang, Lijun
;
Guo, Chuanlong
;
Li, Xiuxue
;
Yu, Xuemin
;
Li, Xiangqian
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/12/11
Bromophenol-thiazolylhydrazone hybrids
Synthesis
Multifunctional
agents
eIF4E/eIF4G interaction
Autophagy
ROS
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