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科研机构
上海药物研究所 [972]
内容类型
期刊论文 [599]
项目 [373]
发表日期
2021 [972]
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浏览/检索结果:
共972条,第1-10条
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发表日期:2021
专题:上海药物研究所
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A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters
期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256
作者:
Dong, Lei
;
Zhang, Min-Yu
;
Han, Hai-Hao
;
Zang, Yi
;
Chen, Guo-Rong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/01/18
Remodeling immune microenvironment in periodontitis using resveratrol liposomes as an antibiotic-free therapeutic strategy
期刊论文
Journal of Nanobiotechnology, 2021, 卷号: 19, 期号: 1
作者:
Shi,Junyu
;
Zhang,Yi
;
Zhang,Xiaomeng
;
Chen,Ruiying
;
Wei,Jianxu
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/04
Resveratrol
Macrophage
Periodontitis
Liposome
Immune microenvironment
Local delivery
A simple and effective method for identification of Fraxini Cortex from different sources by multi-mode fingerprint combined with chemometrics
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 16
作者:
Long, Huali
;
Yao, Shuai
;
Tian, Wenshuai
;
Hou, Jinjun
;
Lei, Min
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/01/18
chemometrics
Fraxini Cortex
high-performance thin-layer chromatography
multi-mode fingerprint
ultra-high-performance liquid chromatography
Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
Shanghai Science and Technology Committee in China[21S11903100]
项目
项目编号: 21S11903100, 资助机构: Shanghai Science and Technology Committee in China, 2021-
-
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  |  
浏览/下载:2/0
  |  
提交时间:2022/01/18
Science and Technology Commission of Shanghai Municipality[20JC1418000]
项目
项目编号: 20JC1418000, 资助机构: Science and Technology Commission of Shanghai Municipality, 2021-
-
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2022/01/18
National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China[2019ZX09301157-003]
项目
项目编号: 2019ZX09301157-003, 资助机构: National Science & Technology Major Project Key New Drug Creation and Manufacturing Program, China, 2021-
-
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2022/01/18
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:
Yang, Xiangbo
;
Lu, Huimin
;
Xie, Hang
;
Zhang, Binbin
;
Nie, Tianqing
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/01/18
Binding studies
Drug discovery
Necroptosis
RIPK1 inhibitors
Sepsis
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
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  |  
浏览/下载:61/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences[XDA12050202]
项目
项目编号: XDA12050202, 资助机构: Personalized Medicines-Molecular Signature-based Drug Discovery and Development Strategic Priority Research Program of the Chinese Academy of Sciences, 2021-
-
收藏
  |  
浏览/下载:164/0
  |  
提交时间:2021/05/24
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