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科研机构
上海药物研究所 [53]
内容类型
期刊论文 [52]
会议论文 [1]
发表日期
2016 [53]
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共53条,第1-10条
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发表日期:2016
专题:上海药物研究所
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Miltirone protects human EA.hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 dependent pathway
期刊论文
PHYTOMEDICINE, 2016, 卷号: 23, 期号: 14, 页码: 1806-1813
作者:
Zhang, Liu
;
Zhang, Hui
;
Li, Xueyan
;
Jia, Bingjie
;
Yang, Yuyu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Miltirone
Nrf2
HO-1
Endothelial dysfunction
Oxidative stress
Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in Rats
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2016, 卷号: 9
作者:
Yang, Xiaoyu
;
Wu, Qimei
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
preconditioning (PC)
HDAC3
MCAO
RGFP966
calpain
Propofol inhibits hERG K+ channels and enhances the inhibition effects on its mutations in HEK293 cells
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 卷号: 791, 页码: 168-178
作者:
Han, Sheng-Na
;
Jing, Ying
;
Yang, Lin-Lin
;
Zhang, Zhao
;
Zhang, Li-Rong
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Propofol
QT prolongation
Human ether-a-go-go-related gene (hERG)
Protein trafficking
Gene mutation
Comparative pharmacokinetic analysis of extracts of crude and wine-processed Dipsacus asper in rats by a sensitive ultra performance liquid chromatography-tandem mass spectrometry approach
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1036, 页码: 33-41
作者:
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Dipsacus asper
Wine-processed
UPLC-MS/MS
Pharmacokinetics
kappa Opioid receptor activation in different brain regions differentially modulates anxiety-related behaviors in mice
期刊论文
NEUROPHARMACOLOGY, 2016, 卷号: 110, 页码: 92-101
作者:
Wang, Yu-Jun
;
Hang, Ai
;
Lu, Yu-Chen
;
Long, Yu
;
Zan, Gui-Ying
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
kappa Opioid receptor
pERK1/2
Region-specific
Dual effects
Anxiety
Chlorogenic acid analogues from Gynura nepalensis protect H9c2 cardiomyoblasts against H2O2-induced apoptosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1413-1422
作者:
Yu, Bang-wei
;
Li, Jin-long
;
Guo, Bin-bin
;
Fan, Hui-min
;
Zhao, Wei-min
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
chlorogenic acid analogues
Gynura nepalensis
cardiomyocytes
oxidative stress
ROS
apoptosis
epigallocatechin gallate
ERK/JNK pathway
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells
期刊论文
BRAIN RESEARCH, 2016, 卷号: 1649, 页码: 123-131
作者:
Hu, Yang-ye
;
Wang, Yuan
;
Liang, Shuang
;
Yu, Xue-li
;
Zhang, Lei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Senkyunolide I
Microglial cells
Oxygen-glucose deprivation/reoxygenation
TLR4/NF-kappa B pathway
HSF-1/Hsp70
Betulin attenuates atherosclerosis in apoE(-/-) mice by up-regulating ABCA1 and ABCG1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1337-1348
作者:
Gui, Yu-zhou
;
Yan, Hong
;
Gao, Fei
;
Xi, Cong
;
Li, Hui-hui
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
atherosclerosis
macrophage
betulin
atorvastatin
T0901317
25-OH cholesterol
ATP-binding cassette transporter A1
ATP-binding cassette transporter G1
sterol-responsive element-binding protein
OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1359-1369
作者:
Ma, Shan-yao
;
Ning, Meng-meng
;
Zou, Qing-an
;
Feng, Ying
;
Ye, Yang-liang
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
OL3
MN6
linagliptin
TGR5 agonist
DPP4 inhibitor
GLP-1
low-absorbed
gallbladder filling
type 2 diabetes mellitus
Novel and Neuroprotective Tetranortriterpenoids from Chinese Mangrove Xylocarpus granatum Koenig
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Zhou, Zhen-Fang
;
Kurtan, Tibor
;
Mandi, Attila
;
Gu, Yu-Cheng
;
Yao, Li-Gong
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
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