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水生生物研究所 [14]
上海药物研究所 [7]
中国医学科学院 北京... [5]
北京大学 [2]
中南大学 [2]
复旦大学上海医学院 [2]
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期刊论文 [33]
会议论文 [3]
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Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237
作者:
Liang, Xuewu
;
Sun, Chenxia
;
Li, Chunpu
;
Yu, Haolan
;
Wei, Xiaohui
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/08/17
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
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  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14
作者:
Chen, Yun
;
Bai, Gang
;
Ning, Yi
;
Cai, Shi
;
Zhang, Tao
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  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
lnterleukin-1 receptor associated kinase 4
Imidazol1,2-6]pyridazine
Diffuse large B-cell lymphoma
Drug design
Antitumor agents
Elevated levels of pre-treatment lactate dehydrogenase are an unfavorable predictor factor in patients with EML4-ALK rearrangement non-small cell lung cancer treated with crizotinib
期刊论文
2019, 卷号: 11, 页码: 8191-8200
作者:
Liang Hongge
;
Ma Di
;
Xu Yan
;
Zhao Jing
;
Chen Minjiang
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  |  
浏览/下载:28/0
  |  
提交时间:2020/01/03
crizotinib
echinoderm microtubule-associated protein-like 4–anaplastic lymphoma kinase
lactate dehydrogenase
non-small cell lung cancer
progression-free survival
Deoxynivalenol decreased the growth performance and impaired intestinal physical barrier in juvenile grass carp (Ctenopharyngodon idella)
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 80, 期号: 1, 页码: 376-391
作者:
Huang, Chen
;
Wu, Pei
;
Jiang, Wei-Dan
;
Liu, Yang
;
Zeng, Yun-Yun
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/07/03
Deoxynivalenol
Grass carp (Ctenopharyngodon idella)
Intestine
Oxidative damage
Apoptosis
Tight junctions
Deficiency of dietary pyridoxine disturbed the intestinal physical barrier function of young grass carp (Ctenopharyngodon idella)
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 74, 期号: 1, 页码: 459-473
作者:
Wu, Pei
;
Zheng, Xin
;
Zhou, Xiao-Qiu
;
Jiang, Wei-Dan
;
Liu, Yang
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  |  
浏览/下载:56/0
  |  
提交时间:2019/07/03
Pyridoxine deficiency
Grass carp (Ctenopharyngodon idella)
Intestine
Antioxidant
Apoptosis
Tight junction
The impaired immune function and structural integrity by dietary iron deficiency or excess in gill of fish after infection with Flavobacterium columnare: Regulation of NF-kappa B, TOR, JNK, p38MAPK, Nrf2 and MLCK signalling
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 74, 期号: 1, 页码: 593-608
作者:
Guo, Yan-Lin
;
Wu, Pei
;
Jiang, Wei-Dan
;
Liu, Yang
;
Kuang, Sheng-Yao
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/07/03
Iron
Grass carp (Ctenopharyngodon idella)
Gill
Immune function
Structural integrity
Sodium butyrate enhanced physical barrier function referring to Nrf2, JNK and MLCK signaling pathways in the intestine of young grass carp (Ctenopharyngodon idella)
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 73, 期号: 1, 页码: 121-132
作者:
Wu, Pei
;
Tian, Li
;
Zhou, Xiao-Qiu
;
Jiang, Wei-Dan
;
Liu, Yang
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/07/03
Sodium butyrate
Intestinal physical barrier
Nrf2
JNK
Grass carp (Ctenopharyngodon idella)
A Global, Randomized, Placebo-Controlled, Phase 3 Study of Ibrutinib Plus Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (RCHOP) in Patients with Previously Untreated Non-Germinal Center B-Cell-like (GCB) Diffuse Large B-Cell Lymphoma (DLBCL)
会议论文
作者:
Duehrsen, Ulrich
;
Younes, Anas
;
Sehn, Laurie H.
;
Johnson, Peter
;
Zinzani, Pier Luigi
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Galangin (GG) combined with cisplatin (DDP) to suppress human lung cancer by inhibition of STAT3-regulated NF-κB and Bcl-2/Bax signaling pathways
期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 97, 页码: 213-224
作者:
Yu, Shuo
;
Gong, Lian-sheng*
;
Li, Nian-feng
;
Pan, Yi-feng
;
Zhang, Lun
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/03
MTT
3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide
GG
Galangin
DDP
cisplatin
STAT3
signal transducers and activation of transcription
LC
Lung cancer
MDR
multidrug resistance
NSCL
Cnon-small cell lung cancer
Bcl-2
B-cell leukemia/lymphoma 2
Bax
bcl-2-like protein
TRAIL
TNF-related apoptosis-inducing ligand
NF-κB
nuclear factor kappa-light-chain-enhancer of activated B cells
IκBα
inhibitor of NF-κBα
Cyto-c
cytochrome c
Lung cancer
Galangin
Cisplatin
p-STAT3/p65
Bcl-2
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