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2-Oxo-3,4-dihydropyrimido[4,5-d] pyrimidines as new reversible inhibitors of EGFR C797S (Cys797 to Ser797) mutant 期刊论文
CHINESE CHEMICAL LETTERS, 2020, 卷号: 31, 期号: 5, 页码: 1281-1287
作者:  Hu, Xianglong;  Xun, Qiuju;  Zhang, Tao;  Zhu, Su-Jie;  Li, Qian
收藏  |  浏览/下载:45/0  |  提交时间:2020/07/01
Mn-Catalyzed Dehydrocyanative Transannulation of Heteroarenes and Propargyl Carbonates through C-H Activation: Beyond the Permanent Directing Effects of Pyridines/Pyrimidines 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 卷号: 58, 期号: 15, 页码: 5090-5094
作者:  Xu, Youwei;  Li, Xingwei;  Zheng, Guangfan;  Sun, Jiagiong;  Zhai, Shuailei
收藏  |  浏览/下载:57/0  |  提交时间:2019/06/20
Follow on-based optimization of the biphenyl-DAPYs as HIV-1 nonnucleoside reverse transcriptase inhibitors against the wild-type and mutant strains 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 89
作者:  Zhuang, Chunlin;  Sang, Yali;  Pannecouque, Christophe;  Han, Sheng;  Han, Shuwen
收藏  |  浏览/下载:25/0  |  提交时间:2019/12/05
Towards to potential 2-cyano-pyrimidines cathepsin-K inhibitors: An in silico design and screening research based on comprehensive application of quantitative structure-activity relationships, molecular docking and ADMET prediction 期刊论文
2019, 卷号: 1195, 页码: 914-928
作者:  Wang, Jiaolong[1];  Peng, Wei[1];  Li, Xinyu[1];  Fan, Wenxiang[1];  Wei, Daneng[1]
收藏  |  浏览/下载:29/0  |  提交时间:2019/12/16
Transition-metal-free selective pyrimidines and pyridines formation from aromatic ketones, aldehydes and ammonium salts 期刊论文
GREEN CHEMISTRY, 2019, 卷号: 21, 期号: 19, 页码: 5201-5206
作者:  Chen, Jinjin;  Meng, Huanxin;  Zhang, Feng*;  Xiao, Fuhong;  Deng, Guo-Jun*
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/23
Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands 期刊论文
CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463
作者:  Qian, Hai-Yan;  Wang, Zhi-Long;  Chen, Li-Li;  Pan, You-Lu;  Xie, Xiao-Yu
收藏  |  浏览/下载:90/0  |  提交时间:2019/01/08
Facile Synthesis of Chiral Cyclic Ureas through Hydrogenation of 2-Hydroxypyrimidine/Pyrimidin-2(1H)-one Tautomers 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 20, 页码: 5853-5857
作者:  Shi, Lei;  Feng, Guang-Shou;  Chen, Mu-Wang;  Zhou, Yong-Gui
收藏  |  浏览/下载:16/0  |  提交时间:2019/06/20
Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 6, 页码: 2353-2371
作者:  Xun, Qiuju;  Zhang, Zhang;  Luo, Jinfeng;  Tong, Linjiang;  Huang, Minhao
收藏  |  浏览/下载:39/0  |  提交时间:2019/01/08
Oral administration of indole substituted dipyrido[2,3-d]pyrimidine derivative exhibits anti-tumor activity via inhibiting AKT and ERK1/2 on hepatocellular carcinoma. 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018
作者:  Yao, Hong;  Yan, Hongru;  Gao, Xiaoge;  Zhu, Songlei;  Cen, Lanqi
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/31
Synthesis and anticancer activity evaluation of novel azacalix[2]arene[2]pyrimidines 期刊论文
2018, 卷号: 151, 页码: 214-225
作者:  Addepalli, Yesu;  Yang, Xiaohong;  Zhou, Minghui;  Reddy, D. Prabhakar;  Zhang, Shao-Lin
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/28


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