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上海药物研究所 [12]
山东大学 [3]
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期刊论文 [20]
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Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 216, 页码: 20
作者:
Gao, Dingding
;
Jin, Nan
;
Fu, Yixian
;
Zhu, Yueyue
;
Wang, Yujie
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/06/11
STAT3 signaling pathway
Benzothiazole
Rational design
Antitumor activity
Molecular docking
3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586
作者:
Shan, Hui
;
Yao, Sheng
;
Ye, Yang
;
Yu, Qiang
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
JAK/STAT
3-deoxy-2 beta,16-dihydroxynagilactone E
tyrosine kinase inhibitor
allosteric inhibitor
cancer
The Protective Effect of Magnesium Lithospermate B on Hepatic Ischemia/Reperfusion via Inhibiting the Jak2/Stat3 Signaling Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 13
作者:
Zhang, Ning
;
Han, Li
;
Xue, Yaru
;
Deng, Qiangqiang
;
Wu, Zhitao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
magnesium lithospermate B
hepatic ischemia/reperfusion
acute injury
anti-inflammation
Jak2/Stat3 signaling pathway
Synthetic derivatives of the natural product 13-amino 2-desoxy-4-epi-pulchellin inhibit STAT3 signaling and induce G2/M arrest and death of colon cancer cells
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 782-785
作者:
Niu, Junxing
;
Huang, Hui
;
Wang, Fei
;
Zhang, Xianjing
;
Liu, Yi
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Sesquiterpene-lactone
JAK2/STAT3
Michael addition reaction
Antitumor
Colorectal carcinoma
Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway
期刊论文
Journal of Orthopaedic Translation, 2019
作者:
Cheng W.-X.
;
Huang H.
;
Chen J.-H.
;
Zhang T.-T.
;
Zhu G.-Y.
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/11
Angiogenesis
Genistein
Rheumatoid arthritis
3deoxy216dihydroxynagilactoneeanaturalcompoundfrompodocarpusnagipreferentiallyinhibitsjak2stat3signalingbyallostericallyinteractingwiththeregulatorydomainofjak2andinducesapoptosisofcancercells
期刊论文
actapharmacologicasinica, 2019, 卷号: 40, 期号: 12, 页码: 1578
作者:
Shan Hui
;
Yao Sheng
;
Ye Yang
;
Yu Qiang
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
JAK/STAT
3-deoxy-2β
16-dihydroxynagilactone E
tyrosine kinase inhibitor
allosteric inhibitor
cancer
3-Deoxy-2β,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/ STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells
期刊论文
中国药理学报:英文版, 2019, 卷号: 40.0, 期号: 012, 页码: 1578
作者:
Hui Shan
;
Sheng Yao
;
Yang Ye
;
Qiang Yu
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/12/24
JAK/STAT
3-deoxy-2β,16-dihydroxynagilactone
E
tyrosine
kinase
inhibitor
allosteric
inhibitor
cancer
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway
期刊论文
International immunopharmacology, 2018, 卷号: 64, 页码: 24-32
作者:
Wu, Xiao-Yu
;
Tian, Fang
;
Su, Min-Hui
;
Wu, Min
;
Huang, Yue
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases
期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 6
作者:
Liu, Man
;
Xiao, Chengqian
;
Sun, Mingwei
;
Tan, Minjia
;
Hu, Lihong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
parthenolide
covalent inhibitor
cell death
JAK/STAT3 signaling
Cucurbitacin I inhibits STAT3, but enhances STAT1 signaling in human cancer cells in vitro through disrupting actin filaments
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 3, 页码: 425-437
作者:
Guo, Hui
;
Kuang, Shan
;
Song, Qiao-ling
;
Liu, Man
;
Sun, Xiao-xiao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
cucurbitacin I
cancer cells
STAT1
STAT3
actin
phosphorylation
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