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Chemical synthesis and biological activity of peptides incorporating an ether bridge as a surrogate for a disulfide bond
期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11
作者:
Zhao, Rui
;
Shi, Pan
;
Chen, Junyou
;
Sun, Shuaishuai
;
Chen, Jingnan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/10/26
Synthesis of Disulfide Surrogate Peptides Incorporating Large-Span Surrogate Bridges Through a Native-Chemical-Ligation-Assisted Diaminodiacid Strategy
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 卷号: 59
作者:
Qu, Qian
;
Gao, Shuai
;
Wu, Fangming
;
Zhang, Meng-Ge
;
Li, Ying
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/11/26
chemical protein synthesis
cyclic peptides
disulfides
native chemical ligation
peptides
Cloning, synthesis and functional characterization of a novel α-conotoxin Lt1.3(Article)
期刊论文
Marine Drugs, 2018, 卷号: Vol.16 No.4
作者:
Cai, F.
;
Chen, J.
;
Zhang, L.
;
Liu, Z.
;
Zhou, L.
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  |  
浏览/下载:5/0
  |  
提交时间:2019/04/24
Cloning
GABABR-coupled
Cav2.2
Lt1.3
Synthesis
Α-conotoxins
Α3β2
nAChRs
Upregulation of N-type calcium channels in the soma of uninjured dorsal root ganglion neurons contributes to neuropathic pain by increasing neuronal excitability following peripheral nerve injury
期刊论文
Brain, Behavior, and Immunity, 2018, 卷号: 71, 页码: 52-65
作者:
Jie Yang
;
Man-Xiu Xie
;
Li Hu
;
Xiao-Fang Wang
;
Jie-Zhen Mai
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/06/15
N-type voltage-gated calcium
Dorsal root ganglion
Mechanical allodynia
Excitability
Cytokine
Im10A, a short conopeptide isolated from Conus imperialis and possesses two highly concentrated disulfide bridges and analgesic activity
期刊论文
PEPTIDES, 2016, 卷号: 81, 页码: 15-20
作者:
Yu, Shuo
;
Du, Tianpeng
;
Liu, Zhuguo
;
Wu, Qiaoling
;
Feng, Guixue
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2016/07/12
Conopeptide
Im10A
Isolation
Synthesis
NMR structure
Analgesic activity
Diaminodiacid Bridges to Improve Folding and Tune the Bioactivity of Disulfide-Rich Peptides
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 卷号: 54, 期号: 48, 页码: 14276-14281
作者:
Guo, Ye
;
Sun, De-Meng
;
Wang, Feng-Liang
;
He, Yao
;
Liu, Lei
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2017/10/26
Disulfide-rich Peptide
Peptide Therapeutics
Peptide Synthesis
Protein Engineering
Protein Folding
Identification of Two Novel O2-Conotoxins from Conus generalis
期刊论文
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2015, 卷号: 21, 期号: 1, 页码: 81-89
作者:
Xu, SQ
;
Shao, XX
;
Yan, MD
;
Chi, CW
;
Lu, AP
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2015/07/22
Conotoxin
O2-superfamily
cDNA cloning
gamma-carboxylation
gamma-carboxyglutamic acid
Conus generalis
A novel 4/6-type alpha-conotoxin ViIA selectively inhibits nAchR α3β2 subtype
期刊论文
Acta Biochimica et Biophysica Sinica, 2015, 卷号: 47, 期号: 12, 页码: 1023-1028
作者:
Li, Liang
;
Liu, Na
;
Ding, Rong
;
Wang, Shuo
;
Liu, Zhuguo
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/27
α-conotoxin
ViIA
cloning
synthesis
α3β2 nAChR subtype
Prediction of Enzyme's Family Based on Protein-Protein Interaction Network
期刊论文
CURRENT BIOINFORMATICS, 2015, 卷号: 10, 期号: 1, 页码: 16-21
作者:
Niu, Bing
;
Lu, Yin
;
Lu, Jing
;
Chen, Fuxue
;
Zhao, Tonghui
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Amino acid frequency
enzyme family classes
jackknife test
PPI network-based method
Characterization of a T-superfamily conotoxin TxVC from Conus textile that selectively targets neuronal nAChR subtypes
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 卷号: 454, 期号: 1, 页码: 151-156
作者:
Wang, Shuo
;
Du, Tianpeng
;
Liu, Zhuguo
;
Wang, Sheng
;
Wu, Ying
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2015/06/24
Conus textile
T-superfamily conotoxin TxVC
Neuronal nicotinic acetylcholine receptor
Selectivity
NMR structure
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