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科研机构
上海药物研究所 [31]
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期刊论文 [31]
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2021 [1]
2020 [3]
2018 [2]
2017 [4]
2016 [4]
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Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 6
作者:
Xiong, Fengmin
;
Ding, Xiaoyu
;
Zhang, Hao
;
Luo, Xiaomin
;
Chen, Kaixian
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/08/17
Monoacylglycerol lipase
Inhibitor
Virtual screening
Inflammation
Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway
期刊论文
CIRCULATION RESEARCH, 2020, 卷号: 127, 期号: 4, 页码: 534-549
作者:
You, Yan
;
Bao, Wei-Lian
;
Zhang, Su-Lin
;
Li, Hai-Dong
;
Li, Hui
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
atherosclerosis
foam cell
lipid metabolism
monocytes
sorting nexin
Integrin beta 3 Deficiency Results in Hypertriglyceridemia via Disrupting LPL (Lipoprotein Lipase) Secretion
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2020, 卷号: 40, 期号: 5, 页码: 1296-1310
作者:
Xiao, Bing
;
Mao, Jianhua
;
Sun, Boyang
;
Zhang, Wei
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/07/01
integrins
lipoprotein lipase
lipoproteins
protein kinase D
thrombasthenia
Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes
期刊论文
ENDOCRINE, 2020, 卷号: 67, 期号: 3, 页码: 587-596
作者:
Dou, Hui-Xia
;
Wang, Ting
;
Su, Hai-Xia
;
Gao, Ding-Ding
;
Xu, Ye-Chun
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
eFABP4
Adipocyte
Differentiation
Lipolysis
Inflammation
Elucidation of lid open and orientation of lipase activated in interfacial activation by amphiphilic environment
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 119, 页码: 1211-1217
作者:
Cheng, Cheng
;
Jiang, Tianyue
;
Wu, Yulu
;
Cui, Lupeng
;
Qin, Song
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Lipase
Amphiphilic media
Interfacial activation
Enhanced digestion inhibition and mucus penetration of F127-modified self-nanoemulsions for improved oral delivery
期刊论文
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 卷号: 13, 期号: 4, 页码: 326-335
作者:
Song, Wenyi
;
Yang, Yuting
;
Yu, Miaorong
;
Zhu, Quanlei
;
Damaneh, Mohammadali Soleimani
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Self-nanoemulsifying system (SNEs)
Oral absorption
Enzymatic degradation
Mucus penetration
Pluronic (R) F127
Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Miao, Chunxiao
;
Lv, Yuanyuan
;
Zhang, Wanli
;
Chai, Xiaoping
;
Feng, Lixing
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/01/08
cancer cachexia
PDTC
C2C12 myotubes
3T3-L1 adipocytes
muscle atrophy
fat lipolysis
Design and synthesis of Atglistatin derivatives as adipose triglyceride lipase inhibitors
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1122-1133
作者:
Jin, Jiyu
;
Huang, Suling
;
Wang, Lei
;
Leng, Ying
;
Lu, Wei
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
adipose triglyceride lipase inhibitors
Atglistatin
structure-activity relationship
thiourea
Asymmetric Total Synthesis of Distaminolyne A and Revision of Its Absolute Configuration
期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 3, 页码: 714-717
作者:
Sun, Dong-Yu
;
Han, Guan-Ying
;
Gong, Jing-Xu
;
Nay, Bastien
;
Li, Xu-Wen
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
Further brominated polyacetylenes with pancreatic lipase inhibitory activity from Chinese marine sponge Xestospongia testudinaria
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 7, 页码: 732-737
作者:
Yang, Min
;
Liang, Lin-Fu
;
Wang, Ting
;
Wang, He-Yao
;
Liu, Hai-Li
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Brominated polyacetylene
sponge
Xestospongia testudinaria
pancreatic lipase inhibitory activity
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