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科研机构
上海药物研究所 [14]
内容类型
期刊论文 [14]
发表日期
2021 [2]
2020 [3]
2019 [2]
2017 [1]
2016 [2]
2015 [1]
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Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
收藏
  |  
浏览/下载:149/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Structurally diverse halosesquiterpenoids from the red alga Laurencia composita Yamada
期刊论文
FITOTERAPIA, 2020, 卷号: 146, 页码: 9
作者:
Hu, Zhi-Biao
;
Yu, Xiao-Qing
;
Wang, Bin
;
Liu, Ai-Hong
;
Zhao, Tian-Sheng
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/24
Laurencia composita
Chamigrane sesquiterpenoids
Bisabolane sesquiterpenoids
Nerolidol derivative
Modified Mosher's method
Antifungal activity
Antibacterial activity
Integrative Proteomic Characterization of Human Lung Adenocarcinoma
期刊论文
CELL, 2020, 卷号: 182, 期号: 1, 页码: 245-+
作者:
Xu, Jun-Yu
;
Zhang, Chunchao
;
Wang, Xiang
;
Zhai, Linhui
;
Ma, Yiming
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/12/24
Structural Insight into the Interactions between Structurally Similar Inhibitors and SIRT6
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 7, 页码: 15
作者:
Zhao, Shuang
;
Zhu, Yan-Yan
;
Wang, Xiao-Yu
;
Liu, Yong-Sheng
;
Sun, Yun-Xiang
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
SIRT6
inhibitor
nature molecule
molecular dynamics simulation
scutellarin
hydrophobic interactions
pi-stacking interactions
binding sites
Comparison of high-resolution synchrotron-radiation-based phase-contrast imaging and absorption-contrast imaging for evaluating microstructure of vascular networks in rat brain: from 2D to 3D views
期刊论文
JOURNAL OF SYNCHROTRON RADIATION, 2019, 卷号: 26, 页码: 2024-2032
作者:
Li, Hong-Lei
;
Ding, Hui
;
Yin, Xian-Zhen
;
Chen, Zhuo-Hui
;
Tang, Bin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
2D
3D
brain
microtomography
synchrotron radiation
vascular network
Synchrotron radiation micro-tomography for high-resolution neurovascular network morphology investigation
期刊论文
JOURNAL OF SYNCHROTRON RADIATION, 2019, 卷号: 26, 页码: 607-618
作者:
Cao, Yong
;
Zhang, Mengqi
;
Ding, Hui
;
Chen, Zhuohui
;
Tang, Bin
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
high-resolution
imaging
neurovascular network
3D
New monoterpenoid oxindole alkaloid derivatives from the stems of Uncaria hirsuta Havil. and their cytotoxicity and tandem mass spectrometric fragmentation
期刊论文
FITOTERAPIA, 2017, 卷号: 116, 页码: 85-92
作者:
Pan, Hui-qin
;
Yang, Wen-zhi
;
Zhao, Dan
;
Luo, Cheng
;
Yao, Chang-liang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Uncaria hirsuta
Monoterpenoid oxindole alkaloid
MDA-MB-231
Collision-induced dissociation
Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 124, 页码: 981-991
作者:
Ma, Guang-Hui
;
Ye, Yan
;
Zhang, Dan
;
Xu, Xin
;
Si, Pei
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
HFMD
EV71 3C(Pro)
Non-peptidyl inhibitor
Virtual screening
Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes
期刊论文
CELL RESEARCH, 2016, 卷号: 26, 期号: 2, 页码: 206-216
作者:
Shi, Xiao-Lei
;
Gao, Yimeng
;
Yan, Yupeng
;
Ma, Hucheng
;
Sun, Lulu
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
acute liver failure
functional hepatocytes
bioartificial liver
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