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科研机构
上海药物研究所 [8]
内容类型
期刊论文 [8]
发表日期
2021 [2]
2018 [2]
2017 [3]
2016 [1]
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专题:上海药物研究所
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Anti-neuroinflammatory activity of Shenqi Fuzheng Injection and its main active constituents
期刊论文
BIOSCIENCE TRENDS, 2021, 卷号: 15, 期号: 4, 页码: 231-239
作者:
Wang, Wenwen
;
Zhang, Zijia
;
Deng, Yanping
;
Yang, Zhixin
;
Hou, Jinjun
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/11/04
Neuroinflammation
Shenqi Fuzheng Injection (SFI)
Arginase 1 (Arg1)
Transforming growth factor beta-1 (Tgfb1)
microglia
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:
Chen, Jingjing
;
Li, Yalei
;
Zhang, Jie
;
Zhang, Minmin
;
Wei, Aihuan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
HDAC
BRD4
Selective dual inhibitors
Anticancer
Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents
期刊论文
ACS chemical neuroscience, 2018
作者:
Xu, Yixiang
;
Zhang, Jian
;
Wang, Huan
;
Mao, Fei
;
Bao, Keting
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/01/08
Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 12, 页码: 3117-3125
作者:
Liu, Wenwen
;
Wang, Huan
;
Li, Xiaokang
;
Xu, Yixiang
;
Zhang, Jian
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Depression
Cognitive impairment
Multitarget-directed ligand
5-HT1A agonist
5-HT reuptake inhibition
ChE inhibition
Novel Vilazodone Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2017, 卷号: 8, 期号: 12, 页码: 2708-2721
作者:
Li, Xiaokang
;
Wang, Huan
;
Xu, Yixiang
;
Liu, Wenwen
;
Gong, Qi
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
depression
multitarget-directed ligand
ChE inhibition
5-HT1A agonist
5-HT reuptake inhibition
Design, Synthesis, and Biological Evaluation of the First c-Met/HDAC Inhibitors Based on Pyridazinone Derivatives
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 8, 页码: 830-834
作者:
Lu, Dong
;
Yan, Juan
;
Wang, Lang
;
Liu, Hongchun
;
Zeng, Limin
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Dual c-Met/HDAC inhibitor
hybrid
designed multiple ligand (DML)
Strategy for comparative untargeted metabolomics reveals honey markers of different floral and geographic origins using ultrahigh-performance liquid chromatography-hybrid quadrupole-orbitrap mass spectrometry
期刊论文
Journal of chromatography. A, 2017, 卷号: 1499, 页码: 78-89
作者:
Li, Yi
;
Jin, Yue
;
Yang, Shupeng
;
Zhang, Wenwen
;
Zhang, Jinzhen
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Hybrid quadrupole-orbitrap mass spectrometry analysis with accurate-mass database and parallel reaction monitoring for high-throughput screening and quantification of multi-xenobiotics in honey
期刊论文
Journal of chromatography. A, 2016, 卷号: 1429, 页码: 119-26
作者:
Li, Yi
;
Zhang, Jinzhen
;
Jin, Yue
;
Wang, Lin
;
Zhao, Wen
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
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