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科研机构
上海药物研究所 [34]
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期刊论文 [34]
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2021 [3]
2020 [5]
2019 [2]
2018 [2]
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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
A homogeneous time-resolved fluorometric energy transfer assay for the binding assessment of FcRn with IgG antibodies
期刊论文
JOURNAL OF IMMUNOLOGICAL METHODS, 2021, 卷号: 499, 页码: 6
作者:
Song, Yakai
;
Deng, Xiaojie
;
Shi, Wei
;
Tang, Feng
;
Huang, Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
FcRn
TR-FRET
mAb
ADC
Pharmacokinetics
TANK-binding kinase 1 (TBK1): An emerging therapeutic target for drug discovery
期刊论文
DRUG DISCOVERY TODAY, 2021, 卷号: 26, 期号: 10, 页码: 2445-2455
作者:
Xiang, Shuang
;
Song, Shukai
;
Tang, Haotian
;
Smaill, Jeff B.
;
Wang, Aiqun
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/12/01
Antibiotic resistance
Computational biology
Databases
In silico tools
Capsaicin derivatives with nitrothiophene substituents: Design, synthesis and antibacterial activity against multidrug-resistant S. aureus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 198, 页码: 11
作者:
Wang, Zhi-Cheng
;
Wei, Bingyan
;
Pei, Fang-Ning
;
Yang, Teng
;
Tang, Jie
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/12/24
Capsaicin
Nitrothiophene
Multidrug-resistant S. aureus
Antibacterial agent
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma
Sinulasterols A-C, three new bioactive oxygenated steroids from the South China Sea soft coral Sinularia depressa
期刊论文
STEROIDS, 2020, 卷号: 157, 页码: 5
作者:
Yang, Min
;
Cui, Wan-Xiang
;
Li, Heng
;
Li, Song-Wei
;
Yao, Li-Gong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Sinularia
Oxygenated steroids
Anti-inflammatory
Introducing "Future of Biochemistry 2020: The Asia-Pacific Issue"
期刊论文
BIOCHEMISTRY, 2020, 卷号: 59, 期号: 1, 页码: 1-7
作者:
Ananthanarayanan, Vaishnavi
;
Chattopadhyay, Kausik
;
Chen, Lei
;
Cheng, Liang
;
Edgington-Mitchell, Laura
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Polycyclic furanobutenolide-derived norditerpenoids from the South China Sea soft corals Sinularia scabra and Sinularia polydactyla with immunosuppressive activity
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 94, 页码: 8
作者:
Cui, Wan-Xiang
;
Yang, Min
;
Li, Heng
;
Li, Song-Wei
;
Yao, Li-Gong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Norditerpenoids
Sinularia
Absolute configuration
Immunosuppressive activity
Comparison of high-resolution synchrotron-radiation-based phase-contrast imaging and absorption-contrast imaging for evaluating microstructure of vascular networks in rat brain: from 2D to 3D views
期刊论文
JOURNAL OF SYNCHROTRON RADIATION, 2019, 卷号: 26, 页码: 2024-2032
作者:
Li, Hong-Lei
;
Ding, Hui
;
Yin, Xian-Zhen
;
Chen, Zhuo-Hui
;
Tang, Bin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
2D
3D
brain
microtomography
synchrotron radiation
vascular network
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:
Jin, Nan
;
Bi, Aiwei
;
Lan, Xiaojing
;
Xu, Jun
;
Wang, Xiaomin
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/07/01
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