×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [44]
内容类型
期刊论文 [43]
会议论文 [1]
发表日期
2021 [9]
2020 [1]
2019 [7]
2018 [5]
2017 [8]
2016 [1]
更多...
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共44条,第1-10条
帮助
限定条件
专题:上海药物研究所
第一署名单位
第一作者单位
通讯作者单位
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence
期刊论文
NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089
作者:
Bai, Xiangd
;
Wang, Hanchen
;
Ma, Liya
;
Xu, Yongchao
;
Gan, Jiefeng
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/01/18
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:
Wei, Dan
;
Wang, Hanlin
;
Zeng, Qinghe
;
Wang, Wenjing
;
Hao, Bingbing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/16
Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663
作者:
Han, Xu
;
Song, Ning
;
Saidahmatov, Abdusaid
;
Wang, Peipei
;
Wang, Yong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/12/16
Rearranged Diels-Alder Adducts and Prenylated Flavonoids as Potential PTP1B Inhibitors from Morus nigra
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 8, 页码: 2303-2311
作者:
Qu, Ke-Jun
;
Wang, Bin
;
Jiang, Chang-Sheng
;
Xie, Bao-Gang
;
Liu, Ai-Hong
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2021/11/04
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:
Yang, Xiangbo
;
Wang, Zhijia
;
Pei, Yuan
;
Song, Ning
;
Xu, Lei
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/08/17
SHP2 degradation
Proteolysis targeting chimera (PROTAC)
Thalidomide-based heterobifunctional molecules
E3 ubiquitin ligase
CRBN
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia
期刊论文
CHEMMEDCHEM, 2021, 页码: 12
作者:
Jin, Tingting
;
Wang, Peipei
;
Long, Xiubing
;
Jiang, Kailong
;
Song, Pinrao
收藏
  |  
浏览/下载:133/0
  |  
提交时间:2021/05/24
CHK1 inhibitor
diaminopyrimidine
DNA damage response
oral bioavailability
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:
Qian, Hongjie
;
Chen, Qian
;
Lang, Liyu
;
Zou, Yang
;
Pu, Huahua
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/08/17
TPN171H
PDE5 inhibitor
safety
pharmacokinetics
food effect
healthy subjects
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors
期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:
Li, Huiping
;
Liu, Rongrui
;
Shao, Bin
;
Ran, Ran
;
Song, Guohong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Phase I
PARP inhibitor (fluzoparib)
solid tumor
pharmacokinetics
safety
antitumor activity
©版权所有 ©2017 CSpace - Powered by
CSpace