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科研机构
上海药物研究所 [102]
内容类型
期刊论文 [102]
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2021 [7]
2020 [16]
2019 [12]
2018 [9]
2017 [6]
2016 [13]
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Chemistry [3]
Biochemist... [2]
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The Novel Chinese Medicine JY5 Formula Alleviates Hepatic Fibrosis by Inhibiting the Notch Signaling Pathway
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 15
作者:
Fu, Yadong
;
Xiao, Zhun
;
Tian, Xiaoting
;
Liu, Wei
;
Xu, Zhou
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/01/04
traditional Chinese medicine
JY5 formula
fuzheng huayu
hepatic fibrosis
notch signaling pathway
Acylphloroglucinol derivatives with ATP citrate lyase inhibitory activities from Syzygium oblatum Wall
期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 187, 页码: 7
作者:
Huang, Jin-Chang
;
Liu, Yi-Nan
;
Tao, Yun-Hua
;
Chen, Bai-Yu
;
Lei, Chun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/08/17
Syzygium oblatum Wall
Myrtaceae
Acylphloroglucinols
Oblatones A-I
ATP citrate lyase
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation
期刊论文
IMMUNITY, 2021, 卷号: 54, 期号: 4, 页码: 632-+
作者:
Wang, Yan
;
Fu, Zunyun
;
Li, Xutong
;
Liang, Yinming
;
Pei, Siyu
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/06/11
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
收藏
  |  
浏览/下载:147/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation
期刊论文
LIFE SCIENCES, 2021, 卷号: 269, 页码: 8
作者:
Yang, Liu
;
Lei, Xian-Tao
;
Huang, Qi
;
Wang, Ting
;
Sun, Hong-Bin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
GPR120 agonist
Insulin secretion
Anti-inflammation
Insulin resistance
Type 2 diabetes mellitus
A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:
Wang, Zhen
;
Zhang, Hao
;
Chen, Baoen
;
Ouyang, Sisheng
;
Zheng, Tong
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2021/05/24
SPOP
Protein‐
protein interaction
Clear cell Renal Cell Carcinomas
Crystal structure
Peptide inhibitor
Harnessing Genomic Stress for Antitumor Immunity
期刊论文
ANTIOXIDANTS & REDOX SIGNALING, 2020, 页码: 23
作者:
Pu, Congying
;
Tao, Siyao
;
Xu, Jun
;
Huang, Min
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
genomic stress
cancer
genomic instability
antitumor immunity
A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 107-115
作者:
Bian, Youcheng
;
Zeng, Hui
;
Tao, Hong
;
Huang, Lulin
;
Du, Zhenyun
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/12/24
Polygala tenuifolia
Pectin
Pancreatic cancer
Apoptosis
Autophagy
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