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Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载:31/0  |  提交时间:2021/12/01
Kynurenine derivative 3-HAA is an agonist ligand for transcription factor YY1 期刊论文
Journal of Hematology & Oncology, 2021, 卷号: 14, 期号: 1
作者:  Shi,Zhaopeng;  Gan,Guifang;  Xu,Xiang;  Zhang,Jieying;  Yuan,Yuan
收藏  |  浏览/下载:42/0  |  提交时间:2021/11/04
Competitive CatSper Activators of Progesterone from Rhynchosia volubilis 期刊论文
PLANTA MEDICA, 2021, 页码: 10
作者:  Xiang, Jin;  Kang, Hang;  Li, Hong-Gang;  Shi, Yu-Long;  Zhang, Ya-Li
收藏  |  浏览/下载:42/0  |  提交时间:2021/11/04
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei
收藏  |  浏览/下载:51/0  |  提交时间:2021/05/24
Identification of 2-substituted pyrrolo[1,2-b]pyridazine derivatives as new PARP-1 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 31, 页码: 4
作者:  Xiang, Hao-Yue;  Chen, Jian-Yang;  Huan, Xia-Juan;  Chen, Yi;  Gao, Zhao-bing
收藏  |  浏览/下载:14/0  |  提交时间:2021/05/24
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
收藏  |  浏览/下载:33/0  |  提交时间:2021/05/24
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:  Zhang, Xiao-tuan;  Hu, Xiao-bei;  Wang, Han-lin;  Kan, Wei-juan;  Xu, Lei
收藏  |  浏览/下载:49/0  |  提交时间:2020/12/24
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma 期刊论文
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:  Dong, Liang-qing;  Peng, Li-hua;  Ma, Li-jie;  Liu, Dong-bing;  Zhang, Shu
收藏  |  浏览/下载:62/0  |  提交时间:2020/07/01
Synthetic antibodies against BRIL as universal fiducial marks for single?particle cryoEM structure determination of membrane proteins 期刊论文
naturecommunications, 2020, 卷号: 11, 期号: 1, 页码: 1
作者:  Somnath Mukherjee;  Satchal K. Erramilli;  Mark Ammirati;  Frances J. D. Alvarez;  Kimberly F. Fennell
收藏  |  浏览/下载:33/0  |  提交时间:2020/07/01
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1
作者:  Mukherjee, Somnath;  Erramilli, Satchal K;  Ammirati, Mark;  Alvarez, Frances J D;  Fennell, Kimberly F
收藏  |  浏览/下载:3/0  |  提交时间:2021/12/01


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