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科研机构
上海药物研究所 [151]
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期刊论文 [150]
会议论文 [1]
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2021 [17]
2020 [11]
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Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Dong, Ying
;
Tang, Bi-xi
;
Wang, Qi
;
Zhou, Li-wei
;
Li, Cong
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2022/01/04
idiopathic pulmonary fibrosis
DDRs
kinase inhibitor
indazole derivatives
XBLJ-13
nintedanib
bleomycin-induced pulmonary fibrosismouse model
A General Set of DNA-Compatible Reactions for Preparing DNA-Tagged Multisubstituted Pyrroles
期刊论文
BIOCONJUGATE CHEMISTRY, 2021, 卷号: 32, 期号: 11, 页码: 2290-2294
作者:
Qi, Jingjing
;
Liu, Sixiu
;
Seydimemet, Mengnisa
;
Wang, Xuan
;
Lu, Xiaojie
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/01/04
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Wang, Lin
;
Wu, Yan
;
Yao, Sheng
;
Ge, Huan
;
Zhu, Ya
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  |  
浏览/下载:86/0
  |  
提交时间:2021/11/04
SARS-CoV-2
natural products
virtual screening
spike protein
protein-protein interaction modulators
Styryl pyranones with apoptosis activities from the sporocarps of Phellinus igniarius
期刊论文
PHYTOCHEMISTRY LETTERS, 2021, 卷号: 44, 页码: 154-159
作者:
Cao, Yinglong
;
Liu, Yi
;
Wang, Ge
;
Wang, Wenqiong
;
Li, Yougui
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
Phellinus igniarius
Styryl pyranones
Cell apoptosis
DNA-encoded C-H functionality via photoredox-mediated hydrogen atom transformation catalysis
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 42, 页码: 4
作者:
Shan, Jinming
;
Ling, Xing
;
Liu, JiaXiang
;
Wang, Xuan
;
Lu, Xiaojie
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/08/17
Photoredox
Hydrogen atom transfer
N-Boc saturated heterocycle
DNA Encoded Library (DEL)
Neolinulicin A and B from Inula japonica and their anti-inflammatory activities
期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 6
作者:
Wu, Rui-fang
;
Zhou, Bing-duo
;
Wang, Wen-qiong
;
Chen, Tong
;
Xu, Ting-ting
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2021/08/17
Inula japonica
Sesquiterpenes
Anti-inflammation
Anti-inflammatory sesquiterpene dimers and diterpenes from the aerial part of Inula japonica
期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 页码: 8
作者:
Wu, Rui-Fang
;
Wang, Wen-Qiong
;
Zhou, Bing-Duo
;
Wang, Yi
;
Li, Ya-Ding
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/08/17
Anti-inflammation
composite
ent-kaurane diterpenes
Inula japonica
sesquiterpene dimers
Pharmacokinetics-based identification of pseudoaldosterogenic compounds originating from Glycyrrhiza uralensis roots (Gancao) after dosing LianhuaQingwen capsule
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 18
作者:
Lan, Xiao-fang
;
Olaleye, Olajide E.
;
Lu, Jun-lan
;
Yang, Wei
;
Du, Fei-fei
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/06/11
LianhuaQingwen
glycyrrhetic acid
24-hydroxyglycyrrhetic acid
Gancao-induced pseudoaldosteronism
licorice-induced pseudoaldosteronism
11β
-hydroxysteroid dehydrogenase 2
COVID-19
colonic microbiota
A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Ren, Peng-xuan
;
Shang, Wei-juan
;
Yin, Wan-chao
;
Ge, Huan
;
Wang, Lin
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2021/06/11
SARS-CoV-2 inhibitors
RdRp
host ribosome
Virus RNA
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