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浏览/检索结果: 共29条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang 收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei 收藏  |  浏览/下载：45/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   STING inhibitor ameliorates LPS-induced ALI by preventing vascular endothelial cells-mediated immune cells chemotaxis and adhesion 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12 作者:  Wu, Bing;  Xu, Meng-meng;  Fan, Chen;  Feng, Chun-lan;  Lu, Qiu-kai 收藏  |  浏览/下载：59/0  |  提交时间：2022/01/18 acute lung injury  STING  vascular endothelial cells  inflammatory cytokines  chemokines  chemotaxis   Huangjinsan ameliorates adenine-induced chronic kidney disease by regulating metabolic profiling 期刊论文 JOURNAL OF SEPARATION SCIENCE, 2021, 页码: 11 作者:  Guo, Yuejiao;  Liu, Fang;  Chen, MingCang;  Tian, Qiang;  Tian, Xiaoting 收藏  |  浏览/下载：22/0  |  提交时间：2021/12/16 chronic kidney disease  Huangjinsan  metabolomics  renoprotection  traditional Chinese medicine   Amygdalar k-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence 期刊论文 CELL REPORTS, 2021, 卷号: 37, 期号: 5, 页码: 21 作者:  Zan, Gui-Ying;  Wang, Yu-Jun;  Li, Xue-Ping;  Fang, Jun-Fan;  Yao, Song-Yu 收藏  |  浏览/下载：46/0  |  提交时间：2021/12/16 The Novel RET Inhibitor SYHA1815 Inhibits RET-Driven Cancers and Overcomes Gatekeeper Mutations by Inducing G1 Cell-Cycle Arrest through c-Myc Downregulation 期刊论文 MOLECULAR CANCER THERAPEUTICS, 2021, 卷号: 20, 期号: 11, 页码: 2198-2206 作者:  Jiang, Yuchen;  Peng, Xia;  Ji, Yinchun;  Dai, Yang;  Fang, Yanfen 收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16 Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219 作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu 收藏  |  浏览/下载：41/0  |  提交时间：2021/12/01 Hippo pathway  TEAD3  Covalent inhibitor  Palmitoylation inhibitor   The Novel Chinese Medicine JY5 Formula Alleviates Hepatic Fibrosis by Inhibiting the Notch Signaling Pathway 期刊论文 FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 15 作者:  Fu, Yadong;  Xiao, Zhun;  Tian, Xiaoting;  Liu, Wei;  Xu, Zhou 收藏  |  浏览/下载：30/0  |  提交时间：2022/01/04 traditional Chinese medicine  JY5 formula  fuzheng huayu  hepatic fibrosis  notch signaling pathway   Imatinib inhibits the malignancy of hepatocellular carcinoma by suppressing autophagy 期刊论文 EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 906, 页码: 8 作者:  Xiao, Meng-Chao;  Qian, Hui;  Huang, Chen-Kai;  Zheng, Bai-Nan;  Yan, Fang-Zhi 收藏  |  浏览/下载：50/0  |  提交时间：2021/11/04 Imatinib  Autophagy  Hepatocarcinoma  Sorafenib  Synergetic effect   Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers 期刊论文 CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273 作者:  Chen, Zhen-dong;  Chen, Qian;  Zhu, Yun-ting;  Zhang, Yi-fan;  Zhan, Yan 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/04 henagliflozin  food effects  mass balance  pharmacokinetics  SGLT-2 inhibitor