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浏览/检索结果: 共42条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Benzo[c][1,2,5] thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5154-5157 作者:  Wang, Wen-Long;  Chen, Xiao-Yu;  Gao, Ya;  Gao, Li-Xin;  Sheng, Li 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Benzo[c][1,2,5] thiadiazole derivatives  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues 期刊论文 ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 44, 页码: 9352-9361 作者:  Jiang, Hao;  Xing, Jing;  Wang, Chen;  Zhang, Hao;  Yue, Liyan 收藏  |  浏览/下载：108/0  |  提交时间：2019/01/08 Label-free brainwide visualization of senile plaque using cryo-micro-optical sectioning tomography 期刊论文 OPTICS LETTERS, 2017, 卷号: 42, 期号: 21, 页码: 4247-4250 作者:  Luo, Yilin;  Wang, Anle;  Liu, Mengmeng;  Lei, Tian;  Zhang, Xiaochuan 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Dissociative role for dorsal hippocampus in mediating heroin self-administration and relapse through CDK5 and RhoB signaling revealed by proteomic analysis 期刊论文 ADDICTION BIOLOGY, 2017, 卷号: 22, 期号: 6, 页码: 1731-1742 作者:  Chen, Zhong-Guo;  Liu, Xing;  Wang, Weisheng;  Geng, Fan;  Gao, Jing 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 CDK5  dorsal hippocampus  heroin self-administration  label-free proteomic analysis  RhoB  the centrifugal proteomic reactor   Src-dependent phosphorylation of mu-opioid receptor at Tyr(336) modulates opiate withdrawal 期刊论文 EMBO MOLECULAR MEDICINE, 2017, 卷号: 9, 期号: 11, 页码: 1521-1536 作者:  Zhang, Lei;  Kibaly, Cherkaouia;  Wang, Yu-Jun;  Xu, Chi;  Song, Kyu Young 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 lentivirus injection  locus coeruleus  naloxone-precipitated opiate withdrawal  opiate addiction  Src-mediated phosphorylation of MOR at Tyr(336)   Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152 作者:  Wang, Zhengyu;  Shi, Xiaofan;  Zhang, Huan;  Yu, Liang;  Cheng, Yanhua 收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08 Type 2 diabetes mellitus  Hypoglycemia  Dyslipidemia  Glucokinase activators  N-Thiazol-2-yl-benzamides   SYVN1, an ERAD E3 Ubiquitin Ligase, Is Involved in GABA(A)alpha 1 Degradation Associated with Methamphetamine-Induced Conditioned Place Preference 期刊论文 FRONTIERS IN MOLECULAR NEUROSCIENCE, 2017, 卷号: 10 作者:  Jiao, Dong-Liang;  Chen, Yan;  Liu, Yao;  Ju, Yun-Yue;  Long, Jian-Dong 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 methamphetamine  GABA(A)alpha 1  dorsal striatum  ERAD  SYVN1   Isoprenylated phenolic compounds with PTP1B inhibition from Morus alba 期刊论文 FITOTERAPIA, 2017, 卷号: 122, 页码: 138-143 作者:  Huang, Qing-Hua;  Lei, Chun;  Wang, Pei-Pei;  Li, Jing-Ya;  Li, Jia 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Morus alba  Moraceae  Isoprenylated phenolics  Albasins A-D  Protein tyrosine phosphatase 1B   Synthesis and biological evaluation of benzothiazol-based 1,3,4-oxadiazole derivatives as amyloid beta-targeted compounds against Alzheimer's disease 期刊论文 MONATSHEFTE FUR CHEMIE, 2017, 卷号: 148, 期号: 10, 页码: 1807-1815 作者:  Mei, Wen-wen;  Ji, Sha-sha;  Xiao, Wei;  Wang, Xue-dong;  Jiang, Cheng-shi 收藏  |  浏览/下载：62/0  |  提交时间：2019/01/08 Structure-activity relationships  Heterocycles  Drug research  Neuroprotective effects   Antiproliferative Activity of Phenylpropanoids Isolated from Lagotis brevituba Maxim 期刊论文 PHYTOTHERAPY RESEARCH, 2017, 卷号: 31, 期号: 10, 页码: 1509-1520 作者:  Yuan Xiang;  Zhao Jing;  Wang Haixia;  Yu Ruitao;  Wen Huaixiu 收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08 phenylpropanoids  Lagotis brevituba Maxim  antiproliferative  plantamoside