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复旦大学上海医学... [361]
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期刊论文 [355]
会议论文 [6]
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2019 [24]
2018 [40]
2017 [36]
2016 [26]
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专题:复旦大学上海医学院
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A structure-activity relationship study of phenyl sesquiterpenoids on efflux inhibition against Staphylococcus aureus
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 8
作者:
Mu, Qing
;
Sun, Zhong-Lin
;
Liu, Tao
;
Gibbons, Simon
收藏
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浏览/下载:65/0
  |  
提交时间:2019/12/05
Ferula ferulioides
Acetophenone derivatives
Structure-activity relationships
Drug-resistant Staphylococcus aureus
Efflux pump inhibition
Discovery, synthesis, biological evaluation and molecular docking study of (R)-5-methylmellein and its analogs as selective monoamine oxidase A inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 10
作者:
Lei, Xinsheng
;
Hu, Jin-Feng
;
Guan, Hui-Da
;
Wang, Chang-Hong
;
Huang, Chao
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  |  
浏览/下载:45/0
  |  
提交时间:2019/12/05
Natural product
5-Methylmellein
Synthetic analogs
Monoamine oxidase
Inhibitor
Fluorine-18 click radiosynthesis and microPET/CT evaluation of a small peptide-a potential PET probe for carbonic anhydrase IX
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 5
作者:
Cheng, Dengfeng
;
Jia, Lina
;
Li, Xiao
;
Zhang, Lan
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  |  
浏览/下载:47/0
  |  
提交时间:2019/12/05
Carbonic anhydrase IX
F-18-labeling
Tumor hypoxia
PET imaging
Peptide
Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 3
作者:
Shi, Tian-Qi
;
Wang, Yan-Ting
;
Liu, Chang-Hong
;
Zhu, Hai-Liang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Benzimidazole
Benzsulfamide
Pyrazole
Tubulin
Inhibition
Apoptosis
Molecular docking
Seco-4-methyl-DCK derivatives as potent chemosensitizers
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 1
作者:
Guo, Yalan
;
Wan, Qi
;
Chen, Xiaoyu
;
Li, Haihong
;
Morris-Natschke, Susan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Seco-4-methyl-DCK
MDR reversal activity
Chemosensitizer
P-gp
In-depth profiles of bioactive large molecules in saliva secretions of leeches determined by combining salivary gland proteome and transcriptome data
期刊论文
JOURNAL OF PROTEOMICS, 2019, 卷号: 200
作者:
Liu, Zichao
;
Tong, Xiangtong
;
Su, Yuan
;
Wang, Debin
;
Du, Xinru
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
Leech
Proteomic
Medicinal leech therapy
Salivary secretions
Leech sucking pathways
Synthesis and biological evaluation of novel 1-substituted 3-(3-phenoxyprop-1-yn-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amines as potent Bruton's tyrosine kinase (BTK) inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2
作者:
Zheng, Nan
;
Hao, Qun
;
Lin, Kuaile
;
Pan, Jing
;
Li, Yingxia
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  |  
浏览/下载:14/0
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提交时间:2019/12/05
BTK inhibitors
1-Substituted pyrazolo[3,4-d]pyrimidine
Inhibitory activity
B-cell lymphoblastic leukemia
Cytotoxicity
Design, synthesis and biological evaluation of novel indone derivatives as selective ER beta modulators
期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2019, 卷号: 28, 期号: 7
作者:
Liu, Xi-Xi
;
Tang, Mei-Lin
;
Zhong, Chen
;
Tang, Yun
;
Yu, Jian-Ming
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  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Resveratrol oligomer
ER beta
Breast cancer
SERM
Design, synthesis, antitumor activities and biological studies of novel diaryl substituted fused heterocycles as dual ligands targeting tubulin and katanin
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 178
作者:
Gao, Feng
;
Liang, Yuru
;
Zhou, Pengfei
;
Cheng, Jiayi
;
Ding, Kuiling
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/12/05
Imidazo[4,5-c]pyridin-2-one
Tubulin polymerization
Katanin
Antitumor
Discovery of N-indanyl benzamides as potent ROR gamma t inverse agonists
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 167
作者:
Liu, Jin
;
Wang, Yonghui
;
Shao, Liming
;
Liu, Li
;
Tian, Jinlong
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
N-indanyl benzamides
ROR gamma t inverse agonists
Th17 cells
Autoimmune diseases
Binding modes
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