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CORC

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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis 期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:  Han, Yachun;  Xu, Xiaoxuan;  Tang, Chengyuan;  Gao, Peng;  Chen, Xianghui
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/03
ALT  alanine aminotransferase  AST  aspartate aminotransferase  BUN  blood urea nitrogen  BW  body weight  BG  blood glucose  DCFDA  dichlorodihydrofluorescein diacetate  DN  diabetic nephropathy  ECL  enhanced chemiluminescence  EM  electron microscopy  EMT  epithelial–mesenchymal transition  HbA1C  hemoglobin A1c  HE  hematoxylin-eosin  IF  immunofluorescence  IHC  immunohistochemistry  KW  kidney weight  LDL  low-density lipoprotein  MDA  malondialdehyde  MFI  median fluorescence intensity  MMP  mitochondrial transmembrane potential  MMT  methyl methane-thiosulphonate  MPTP  mitochondrial permeability transition pore  MSU  monosodium urate  MtROS  mitochondria reactive oxygen species  PAS  periodic acid-Schiff  Scr  serum creatinine  TC  total cholesterol  TG  triglyceride  TBARS  thiobarbituric acid reactive substances  TPP  triphenylphosphonium  TRX  thioredoxin  TXNIP  thioredoxin-interacting protein  TUNEL  terminal deoxynucleotidyl transferase dUTP nick end-labeling  8-OHdG  8-oxo-deoxyguanosine  UA  uric acid  Diabetic nephropathy  Mitochondria  Reactive oxygen species (ROS)  TRX/TXNIP  NLRP3 inflammasome  MitoQ  
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc 期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:  Yang, Shikun;  Zhao, Li;  Han, Yachun;  Liu, Yu;  Chen, Chao
收藏  |  浏览/下载：24/0  |  提交时间：2019/12/03
DN  diabetic nephropathy  ROS  reactive oxygen species  HG  high-glucose  SIRT1  sirtuin-1  Ac-H3  acetyl-histone H3  STZ  streptozotocin  AMPK  AMP-activated protein kinase  ECM  extracellular matrix  Nox2  NADPH oxidase 2  EMT  tubular epithelial-mesenchymal transition  DAPI  4′,6-diamidino-2-phenylindole 9  DHE  dihydroethidium  NDRD  non-diabetic renal disease  H&E  hematoxylin-eosin  PAS  periodic acid-Schiff  PASM  periodic acid-silver methenamine  IHC  immunohistochemistry  MDA  malondialdehyde  ChIP  chromatin immunoprecipitation  TC  total cholesterol  BUN  blood urea nitrogen  FN  fibronectin  HBA1C  glycosylated hemoglobin  Scr  serum creatinine  TG  triglyceride  Probucol  Renal injury  Diabetic nephropathy  p66Shc  
Long-term exposure to high air pollution induces cumulative DNA damages in traffic policemen 期刊论文
Science of the Total Environment, 2017, 卷号: 593-594, 期号: Volumes 593–594, 页码: 330-336
作者:  Tan, Chaochao;  Lu, Shijie;  Wang, Yupeng;  Zhu, Yan;  Shi, Ting
收藏  |  浏览/下载：1/0  |  提交时间：2019/12/03
The antiviral signaling mediated by black carp MDA5 is positively regulated by LGP2 期刊论文
Fish and Shellfish Immunology, 2017, 卷号: 66, 页码: 360-371
作者:  Liu, Ji;  Li, Jun;  Xiao, Jun;  Chen, Hui;  Lu, Liang
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03
Aucubin and its hydrolytic derivative attenuate activation of hepatic stellate cells via modulation of TGF-β stimulation 期刊论文
Environmental Toxicology and Pharmacology, 2017, 卷号: 50, 页码: 234-239
作者:  Lv, Pei-Yu;  Feng, Han;  Huang, Wei-Hua;  Tian, Ying-Ying;  Wang, Ya-Qin
收藏  |  浏览/下载：1/0  |  提交时间：2019/12/03
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms 期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:  Peng, Mei*;  Darko, Kwame Oteng;  Tao, Ting;  Huang, Yanjun;  Su, Qiongli
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/03
AIs  aromatase inhibitors  AMPK  Adenosine Monophosphate-Activated Protein Kinase  AR  androgen  ATM  Ataxia Telangiectasia Mutated  ATP  Adenosine Triphosphate  BCSS  breast cancer specific survival  CK-MB  Creatine Kinase-MB  CREB1  cAMP Response Element-Binding Protein 1  CSC  cancer stem cell  DFS  disease-free survival  DHFU  dihydrofluorouracil  DPD  dihydropyrimidine dehydrogenase  EpCAM  Epithelial Cell Adhesion Molecule  ER  estrogen  ERCC1  excision repair cross-complementary 1  ERK  extracellular signal-regulated kinases  EZH2  enhancer of zeste homolog 2  FdUMP  fluorodeoxyuridine monophosphate  FdUTP  fluorodeoxyuridine triphosphate  FHC  ferritin heavy chain  FUTP  fluorouridine triphosphate  HbA1C  hemoglobin A1c  HER  Human Epidermal Growth Factor Receptor  HIF-1α  hypoxia-inducible factor-1α  HK  hexokinase  IGF1R  insulin growth factor 1 receptor  LDH  lactate dehydrogenase  MDA  Muscular Dystrophy Association  MMP  Matrix Metallopeptidase  MRP1  multidrug resistance-associated protein 1  mTOR  mammalian target of rapamycin  MTX  methotrexate  NCCN  National Comprehensive Cancer Network  OS  overall survival  pCR  Pathologic Complete Response  PDGFR  platelet-derived growth factor receptors  PFS  progression-free survival  PKA  protein kinase A  PR  progesterone receptor  RFS  relapse-free survival  SOD  superoxide dismutase  TAM  tamoxifen  TCA  tricarboxlic acid  TS  thymidylate synthase  Combination  Mechanisms  Metformin  Chemotherapeutic drugs  
Activation of microbubbles by low-intensity pulsed ultrasound enhances the cytotoxicity of curcumin involving apoptosis induction and cell motility inhibition in human breast cancer MDA-MB-231 cells 期刊论文
Ultrasonics Sonochemistry, 2016, 卷号: 33, 页码: 26-36
作者:  Li, Yixiang;  Wang, Pan;  Chen, Xiyang;  Hu, Jianmin;  Liu, Yichen
收藏  |  浏览/下载：18/0  |  提交时间：2019/12/03
Dermatomyositis, polymyositis and immune-mediated necrotising myopathies 期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2015, 卷号: 1852, 期号: 4, 页码: 622-632
作者:  Luo, Yue-Bei;  Mastaglia, Frank L
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/03
BAFF  B cell-activating factor  BLTK  B lymphoid tyrosine kinase  CCL21  chemokine (C-C motif) ligand 2  CK  creatine kinase  DC  dendritic cell  CTD  connective tissue disease  DFS70  dense fine speckled 70  DM  dermatomyositis  HIV  human immunodeficiency virus  HLA  human leukocyte antigen  HMGCR  3-hydroxy-3-methyl-glutaryl-CoA reductase  HTLV-1  human T cell leukaemia virus  IBM  inclusion body myositis  IFIH1  interferon induced with helicase C domain protein 1  IL  interleukin  IMNM  immune-mediated necrotising myopathies  INF  interferon  IP-10  INFγ-inducible 10-kD protein  ISG15  IFN-stimulated gene 15  I-TAC  IFN-inducible T cell α chemoattractant  LEDGF  lens epithelium-derived growth factor  MAC  membrane attack complex  MCP-1  monocyte chemoattractant protein-1  MCTD  mixed connective tissue disease  MDA5  melanoma differentiation-associated gene 5  MHC  major histocompatibility complex  MIF  macrophage inhibition factor  MIP-1α  macrophage inflammatory protein 1α  miRNA  microRNA  MxA  myxovirus resistance 1 protein  NuRD  nucleosome remodelling deacetylase complex  NXP-2  nuclear matrix protein 2  pDC  plasmacytoid dendritic cell  PKCε  protein kinase C ε type  PLCL1  phospholipase C like-1  PM  polymyositis  PTPN  protein tyrosine phosphatase N22 gene  SRP  signal recognition particle  RNP  ribonuclear protein complex  TIF  transcription intermediary factor  TLR  Toll like receptor  TNF  tumour necrosis factor  VCAM1  vascular cell adhesion molecule 1  VEGF  vascular endothelial growth factor  Idiopathic inflammatory myopathy  Polymyositis  Dermatomyositis  Immune-mediated necrotising myopathy  Autoantibody  
Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by andrographolide via suppression of nuclear factor-kappa B-dependent matrix metalloproteinase-9 expression 期刊论文
Molecular Medicine Reports, 2015, 卷号: 11, 期号: 2, 页码: 1139-1145
作者:  Zhai, Zanjing;  Qu, Xinhua;  Li, Haowei;  Ouyang, Zhengxiao;  Yan, Wei
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/03
Metal chelator combined with permeability enhancer ameliorates oxidative stress-associated neurodegeneration in rat eyes with elevated intraocular pressure 期刊论文
Free Radical Biology and Medicine, 2014, 卷号: 69, 页码: 289-299
作者:  Liu, P;  Zhang, M;  Shoeb, M;  Hogan, D;  Tang, Luosheng
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/03

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