NO  nitric oxide  PGE2  prostaglandin E2  NSAIDs  non-steroidal anti-inflammatory drugs  qRT-PCR  quantitative real-time polymerase chain reaction  LPS  lipopolysaccharide  IFN-γ  interferon γ  G-CSF  granulocyte colony stimulating factor  TNF-α  tumor necrosis factor-α  IL-1β  interleukin-1β  IL-6  interleukin-6  MCP-1  monocyte chemoattractant protein-1  NF-κB  Nuclear factor-κB  IκB  inhibitory protein  IKK  IκB kinase  RPS3  ribosomal protein S3  iNOS  inducible nitric oxide synthase  COX-2  cyclooxygenase-2  PGESs  prostaglandin E2 synthases  mPGES-1  microsomal prostaglandin synthetase-1  mPGES-2  microsomal prostaglandin E synthase-2  cPGES  cytosolic prostaglandin E synthase  MAPK  mitogen-activated protein kinases  ERK  extracellular signal-regulated kinase  JNK  c- Jun N-terminal kinase  PGI2  prostacyclin I2  PGD2  prostaglandin D2  PGF2α  prostaglandin F2α  TXA2  thromboxane A2  Stauntoside B (PubChem CID: 101010462)  Stauntoside B  Cynanchi stauntonii  Lipopolysaccharide  Anti-inflammatory activity  NF-κB  MAPK  

BAFF  B cell-activating factor  BLTK  B lymphoid tyrosine kinase  CCL21  chemokine (C-C motif) ligand 2  CK  creatine kinase  DC  dendritic cell  CTD  connective tissue disease  DFS70  dense fine speckled 70  DM  dermatomyositis  HIV  human immunodeficiency virus  HLA  human leukocyte antigen  HMGCR  3-hydroxy-3-methyl-glutaryl-CoA reductase  HTLV-1  human T cell leukaemia virus  IBM  inclusion body myositis  IFIH1  interferon induced with helicase C domain protein 1  IL  interleukin  IMNM  immune-mediated necrotising myopathies  INF  interferon  IP-10  INFγ-inducible 10-kD protein  ISG15  IFN-stimulated gene 15  I-TAC  IFN-inducible T cell α chemoattractant  LEDGF  lens epithelium-derived growth factor  MAC  membrane attack complex  MCP-1  monocyte chemoattractant protein-1  MCTD  mixed connective tissue disease  MDA5  melanoma differentiation-associated gene 5  MHC  major histocompatibility complex  MIF  macrophage inhibition factor  MIP-1α  macrophage inflammatory protein 1α  miRNA  microRNA  MxA  myxovirus resistance 1 protein  NuRD  nucleosome remodelling deacetylase complex  NXP-2  nuclear matrix protein 2  pDC  plasmacytoid dendritic cell  PKCε  protein kinase C ε type  PLCL1  phospholipase C like-1  PM  polymyositis  PTPN  protein tyrosine phosphatase N22 gene  SRP  signal recognition particle  RNP  ribonuclear protein complex  TIF  transcription intermediary factor  TLR  Toll like receptor  TNF  tumour necrosis factor  VCAM1  vascular cell adhesion molecule 1  VEGF  vascular endothelial growth factor  Idiopathic inflammatory myopathy  Polymyositis  Dermatomyositis  Immune-mediated necrotising myopathy  Autoantibody