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科研机构
上海药物研究所 [55]
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期刊论文 [54]
会议论文 [1]
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2021 [2]
2020 [4]
2019 [4]
2018 [6]
2017 [6]
2016 [8]
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Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2
期刊论文
BLOOD ADVANCES, 2021, 卷号: 5, 期号: 1, 页码: 185-197
作者:
Wu, Wenjun
;
Wang, Weige
;
Franzen, Carrie A.
;
Guo, Hui
;
Lee, Jimmy
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  |  
浏览/下载:44/0
  |  
提交时间:2020/07/01
Mechanism and optimization of supramolecular complexation-enhanced fluorescence spectroscopy for the determination of SN-38 in plasma and cells
期刊论文
LUMINESCENCE, 2020, 页码: 12
作者:
Zhao, Kena
;
Guo, Tao
;
Sun, Xian
;
Xiong, Ting
;
Ren, Xiaohong
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  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
cyclodextrins
inclusion complex
pharmacokinetics
SN‐
38
spectrofluorimetric
transfer
Quantification of microbiota-related phenols and aromatic acids in mouse feces of a diabetic nephropathy model by simultaneous BDAPE derivatization using ultra-performance liquid chromatography-tandem mass spectrometry
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 卷号: 412, 期号: 13, 页码: 3241-3252
作者:
Zheng, Xiaoli
;
Duan, Haonan
;
Lin, Feifei
;
Li, Xiaomei
;
Shen, Jianhua
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  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Phenols
Aromatic acid
Microbiota
Uremic toxin
Simultaneous derivatization
2-Bromo-1-[4-(dimethylamino)phenyl] ethyl ketone
Design of heterostructured hybrids comprising ultrathin 2D bismuth tungstate nanosheets reinforced by chloramphenicol imprinted polymers used as biomimetic interfaces for mass-sensitive detection
期刊论文
COLLOIDS AND SURFACES B-BIOINTERFACES, 2020, 卷号: 188, 页码: 10
作者:
Shaheen, Ayesha
;
Taj, Ayesha
;
Lieberzeit, Peter A.
;
Mujahid, Adnan
;
Hameed, Sadaf
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  |  
浏览/下载:55/0
  |  
提交时间:2020/07/01
Nanomaterials
Nanohybrids
Bismuth tungstate
Molecularly imprinted polymers
Mass-sensitive
Structural basis of Fusarium myosin I inhibition by phenamacril
期刊论文
PLOS PATHOGENS, 2020, 卷号: 16, 期号: 3, 页码: 23
作者:
Zhou, Yuxin
;
Zhou, X. Edward
;
Gong, Yuanping
;
Zhu, Yuanye
;
Cao, Xiaoman
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  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
Simultaneous determination of alflutinib and its active metabolite in human plasma using liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 176, 页码: 6
作者:
Liu, Xiaoyun
;
Li, Wei
;
Zhang, Yifan
;
Jian, Yong
;
Zhao, Qianyu
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  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
LC-MS/MS
Alflutinib
AST2818
Pharmacokinetics
Human plasma
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models
期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:
Liao, Ping
;
Qiu, Yunguang
;
Mo, Yiqing
;
Fu, Jie
;
Song, Zhenpeng
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Fluorescence imaging of a potential diagnostic biomarker for breast cancer cells using a peptide-functionalized fluorogenic 2D material
期刊论文
CHEMICAL COMMUNICATIONS, 2019, 卷号: 55, 期号: 88, 页码: 13235-13238
作者:
Dou, Wei-Tao
;
Liu, Li-Fang
;
Gao, Jie
;
Zang, Yi
;
Chen, Guo-Rong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
Simultaneous determination of imrecoxib and its two active metabolites in plasma of hepatic impairment patients by liquid chromatography-tandem mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2019, 卷号: 1122, 页码: 58-63
作者:
Hou, Xiangyu
;
Dai, Xiaojian
;
Yang, Yong
;
Zhang, Yifan
;
Zhong, Dafang
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Imrecoxib
Imrecoxib active metabolites
Pharmacokinetics
LC-MS/MS
Human
Moderate impairment
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