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科研机构
上海药物研究所 [12]
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期刊论文 [12]
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2021 [1]
2020 [1]
2019 [1]
2018 [3]
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High-density lipoprotein modulates tumor-associated macrophage for chemoimmunotherapy of hepatocellular carcinoma
期刊论文
NANO TODAY, 2021, 卷号: 37, 页码: 11
作者:
Wang, Junyang
;
Zheng, Chao
;
Zhai, Yihui
;
Cai, Ying
;
Lee, Robert J.
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/06/11
Tumor-associated macrophages
High-density lipoproteins
Immunotherapy
Hepatocellular carcinoma
Immunosuppression
Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase
期刊论文
ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003
作者:
Butler, Joshua H.
;
Baptista, Rodrigo P.
;
Valenciano, Ana L.
;
Zhou, Bin
;
Kissinger, Jessica C.
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
Plasmodium
PfPARE
structure-resistance relationship study
Malaria Box
Pathogen Box
lindenane sesquiterpenoid dimers
MUTATIONS IN PLASMODIUM FALCIPARUM PRO-DRUG ACTIVATION AND RESISTANCE ESTERASE MEDIATES RESISTANCE TO A SUB-CLASS OF SESQUITERPENE DIMER ANTIMALARIAL NATURAL PRODUCTS
期刊论文
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2019, 卷号: 101, 页码: 83-83
作者:
Butler, Joshua H.
;
Merino, Emilio F.
;
Baptista, Rodrigo P.
;
Okoro, Judith I.
;
Scales, Ryan M.
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  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
Evaluation of Tolerability, Pharmacokinetics and Pharmacodynamics of Vicagrel, a Novel P2Y12 Antagonist, in Healthy Chinese Volunteers
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Xiaojiao
;
Liu, Ca
;
Zhu, Xiaoxue
;
Wei, Haijing
;
Zhang, Hong
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/01/08
vicagrel
pharmacokinetics
pharmacodynamics
safety
clopidogrel
Predominant contributions of carboxylesterase 1 and 2 in hydrolysis of anordrin in humans
期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 5, 页码: 533-540
作者:
Jiang, Jinfang
;
Chen, Xiaoyan
;
Zhong, Dafang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Anordiol
anordrin
carboxylesterase
drug-drug interaction
hydrolysis in humans
Role of human liver and intestine esterases in drug design and development
期刊论文
Acta Pharmaceutica Sinica, 2018, 卷号: 53, 期号: 2, 页码: 177-185
作者:
Jiang Jinfang
;
Li Xiuli
;
Chen Xiaoyan
;
Zhong Dafang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
carboxylesterase
arylacetamide deacetylase
drug metabolism
drug design
TRPA1 channel mediates organophosphate-induced delayed neuropathy
期刊论文
CELL DISCOVERY, 2017, 卷号: 3
作者:
Ding, Qiang
;
Fang, Sui
;
Chen, Xueqin
;
Wang, Youxin
;
Li, Jian
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
organophosphate
malathion
TOCP
OPIDN
TRPA1
Brominated polyunsaturated lipids from the Chinese sponge Xestospongia testudinaria as a new class of pancreatic lipase inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 79, 页码: 290-297
作者:
Liang, Lin-Fu
;
Wang, Ting
;
Cai, You-Sheng
;
He, Wen-Fei
;
Sun, Peng
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Brominated polyunsaturated lipids
Marine sponge
Xestospongia testudinaria
Pancreatic lipase inhibitory activity
SAR
Non-Covalent Interactions with Aromatic Rings: Current Understanding and Implications for Rational Drug Design
期刊论文
CURRENT PHARMACEUTICAL DESIGN, 2013, 卷号: 19, 期号: 36, 页码: 6522-6533
作者:
Li, Shanshan
;
Xu, Yuan
;
Shen, Qiancheng
;
Liu, Xian
;
Lu, Jing
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
pi-pi interactions
cation-pi interactions
anion-pi interactions
quantum mechanical calculations
crystallographic data mining
rational drug design
Acetylcholine esterase (AChE)
HMG-CoA reductase (HMGR)
serine protease factor Xa (fXa)
Theoretical Study of the Mechanism of Proton Transfer in the Esterase Estb from Burkholderia Gladioli
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2011, 卷号: 115, 期号: 44, 页码: 13019-13025
作者:
Chen, Liang
;
Kong, Xiangqian
;
Liang, Zhongjie
;
Ye, Fei
;
Yu, Kunqian
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
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