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科研机构
西安交通大学 [220]
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期刊论文 [220]
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2019 [3]
2018 [31]
2017 [10]
2016 [12]
2015 [28]
2014 [19]
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Discovery of novel anti-angiogenesis agents. Part 9: Multiplex inhibitors suppressing compensatory activations of RTKs.
期刊论文
European journal of medicinal chemistry, 2019, 卷号: 164, 页码: 440-447
作者:
Shan Yuanyuan
;
Si Ru
;
Wang Jin
;
Zhang Qingqing
;
Zhou Huaxin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/11/19
Anti-angiogenic agents
1,2,3-Triazole
RTK inhibitors
Multi-target
Compensatory activation
Peptide Sequence-Dominated Enzyme-Responsive Nanoplatform for Anticancer Drug Delivery.
期刊论文
Current topics in medicinal chemistry, 2019, 卷号: 19, 页码: 74-97
作者:
Li Yanan
;
Du Liping
;
Wu Chunsheng
;
Yu Bin
;
Zhang Hui
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/11/19
Enzyme-responsive
Targeted drug delivery.
Peptide
Tumor microenvironment
Sequence
Discovery of novel anti-angiogenesis agents. Part 10: Multi-target inhibitors of VEGFR-2, Tie-2 and EphB4 incorporated with 1,2,3-triazol.
期刊论文
European journal of medicinal chemistry, 2019, 卷号: 163, 页码: 1-9
作者:
Pan Xiaoyan
;
Liang Liyuan
;
Si Ru
;
Wang Jin
;
Zhang Qingqing
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/11/19
Anti-angiogenic agents
Triple RTK inhibitors
1,2,3-Triazole
DFG-binding group
Multi-target
HOXA4-Dependent Transcriptional Activation of AXL Promotes Cisplatin-Resistance in Lung Adenocarcinoma Cells.
期刊论文
Anti-cancer agents in medicinal chemistry, 2018, 卷号: 18, 页码: 2062-2067
作者:
Yu Shuo
;
Ren Hui
;
Li Yang
;
Liang Xuan
;
Ning Qian
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/19
cisplatin-resistance
HOXA4
homeobox.
HOXA4-Dependent
Lung adenocarcinoma
AXL
MMP7 Induces T-DM1 Resistance and Leads to The Poor Prognosis of Gastric Adenocarcinoma via a DKK1-Dependent Manner.
期刊论文
Anti-cancer agents in medicinal chemistry, 2018, 卷号: 18, 页码: 2010-2016
作者:
Li Hua
;
Xu Xin
;
Liu Yang
;
Li Shunle
;
Zhang Di
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/19
&beta
-catenin-dependent
Therapeutical target.
DKK1
T-DM1 resistant
MMP7
Gastric adenocarcinoma
Loss of Beclin1 expression and Nrf2 overexpression are associated with poor survival of patients with non-small cell lung cancer.
期刊论文
Anti-cancer agents in medicinal chemistry, 2018, 卷号: 18, 页码: 1680-1687
作者:
Hu Tinghua
;
Yu Shuo
;
Cheng Chuantao
;
Wang Jing
;
Wang Jia
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/11/19
clinicopathological
prognostic
biomarker
Beclin1
non-small cell lung cancer
Nrf2
Novel 4-(2-pyrimidinylamino)benzamide derivatives as potent hedgehog signaling pathway inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 页码: 5029-5036
作者:
Xin, Minhang
;
Zhang, Liandi
;
Tu, Chongxing
;
Tang, Feng
;
Wen, Jun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/19
SAR
In vivo
Hedgehog signaling pathway inhibitors
4-(2-Pyrimidinylamino)benzamide
Discovery of 2-(aminopyrimidin-5-yl)-4-(morpholin-4-yl)-6- substituted triazine as PI3K and BRAF dual inhibitor.
期刊论文
Future medicinal chemistry, 2018, 卷号: 10, 页码: 2445-2455
作者:
Wang Hui-Yan
;
Shen Ying
;
Zhang Hao
;
Hei Yuan-Yuan
;
Zhao Hong-Yi
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/19
BRAF inhibitor
drug design
PI3K inhibitor
antiproliferative effects
PI3K and BRAF dual inhibitor
Design and Synthesis of 3,4-diarylpyrrole Analogues as Potent Topoisomerase Inhibitors
期刊论文
MEDICINAL CHEMISTRY, 2018, 卷号: 14, 页码: 485-494
作者:
Chen, Wang
;
Feng, Zili
;
He, Xu
;
Zhao, Qiang
;
Liang, Qi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/11/19
suzuki coupling
anticancer agent
3,4-diarylpyrrole derivatives
topoisomerase Ii alpha
anti-proliferation activity
human breast cancer
Downregulation of Akt2 attenuates ER stress-induced cytotoxicity through JNK-Wnt pathway in cardiomyocytes
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 页码: 394-399
作者:
Gao, Yan-Xia
;
He, Wen-Ting
;
Pan, Long-Fei
;
Feng, Hui
;
Sun, Jiang-Li
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/11/19
JNK
Akt2
Cardiomyocytes
Wnt
ER stress
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