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科研机构
中南大学 [3]
南华大学 [1]
内容类型
期刊论文 [4]
发表日期
2015 [4]
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Effect of osteopontin on the mRNA expression of ADAMTS4 and ADAMTS5 in chondrocytes from patients with knee osteoarthritis
期刊论文
Experimental and Therapeutic Medicine, 2015, 卷号: 9, 期号: 5, 页码: 1979-1983
作者:
Gao, Shu-Guang
;
Zeng, Chao
;
Song, Yang
;
Tian, Jian
;
Cheng, Chao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
a disintegrin and metalloproteinase with thrombospondin motifs 4
a disintegrin and metalloproteinase with thrombospondin motifs 5
aggrecan
osteoarthritis
osteopontin
Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis
期刊论文
The International Journal of Biochemistry & Cell Biology, 2015, 卷号: 67, 页码: 92-100
作者:
Luo, Yangyang
;
Wang, Yong
;
Shu, Ye
;
Lu, Qianjin
;
Xiao, Rong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/03
SSc
systemic sclerosis
SRC
scleroderma renal crisis
PAH
pulmonary arterial hypertension
SMR
standardized mortality ratio
DNMTs
DNA methyltransferases
SAM
S-adenosyl-methionine
5mC
5-methylcytosine
MBD
methyl-CpG-binding domain
Tet
ten–eleven translocation
HATs
histone acetyltransferases
HDACs
histone deacetylases
MiRNAs
microRNAs
MZ
monozygotic
DZ
dizygotic
MVECs
microvascular endothelial cells
FBs
fibroblasts
JAMs
junctional adhesion molecules
CTGF
connective tissue growth facto
TGF-β
transforming growth factor beta
CCN2
connective tissue growth factor
Fli1
Friend leukemia integration-1
TF
transcription factor
PECAM
platelet/endothelial cell adhesion molecule
PDGF
platelet derived growth factor
S1P1
sphingosin 1 phosphate
CXCL5
CXC chemokine ligand-5
BMPs
bone morphogenetic proteins
BMPRII
bone morphogenetic protein type II receptor
ET-1
endotheline-1
uPA
urokinase-type plasminogen activator
MBD
methyl-CpG-binding domain protein
ICAM
intercellular adhesion molecule
KLF5
Kruppel-like factor 5
Tregs
regulatory T cells
Runx1
Runt-related transcription factor 1
FOXP3
forkhead box protein 3 gene
ECM
extra cellular matrix
PDGF
platelet-derived growth factor
dSSc
diffuse systemic sclerosis
lSSc
limited systemic sclerosis
PCAF
protein-associated factor
Egr-1
early growth response 1
DDR2
discoidin domain receptor 2
TAB1
TGF-β activated kinase 1 binding protein 1
BAFF
B cell-activating factor
TSP-2
thrombospondin-2
MRTSS
Modified Rodnan total skin score
SDAI
Valentini scleroderma disease activity index
HC
healthy controls
SLE
systemic lupus erythematosus
SSD
scleroderma spectrum disorder
MTX
methylaminopterin
CYC
cyclophosphamide
MMF
mycophenolate mofetil
ACE
angiotensin converting enzyme
NO
nitric oxide
Systemic sclerosis
Epigenetic mechanisms
Biomarker
Therapy
Deletion of ADAMTS5 does not affect aggrecan or versican degradation but promotes glucose uptake and proteoglycan synthesis in murine adipose derived stromal cells
期刊论文
Matrix Biology, 2015, 卷号: 47, 页码: 66-84
作者:
Gorski, Daniel J
;
Xiao, Wenfeng
;
Li, Jun
;
Luo, Wei
;
Lauer, Mark
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
A2M
alpha-2-macroglobulin
ADSC
adipose derived stromal cell
Acan
aggrecan
Vcan
versican
CS/DS
chondroitin/dermatan sulfate
DE52
diethyl-amino-ethyl cellulose
ECM
extracellular matrix
HA
hyaluronan
IHC
immunohistochemistry
KO
knockout
LRP1
lipoprotein receptor related protein-1
TGF-β1
transforming growth factor beta-1
BMP7
bone morphogenetic protein 7
TS5
a disintegrin and metalloproteinase with thrombospondin motifs 5
ts5−/−J
TS5 knockout mouse from Jackson Labs
ts5−/−P
TS5 knockout mouse from Lexicon
WT
wild type
ADAMTS5 knock out
ADAMTS5
Aggrecan
Versican
Hyaluronan
Degradation
Adipose derived stromal cells
Mesenchymal stem cells
MicroRNAs: New players in intervertebral disc degeneration
期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 333-341
作者:
Wang, Cheng
;
Wang, Wen-Jun
;
Yan, Yi-Guo
;
Xiang, Yong-Xiao
;
Zhang, Jian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/27
IVD
intervertebral disc
NP
nucleus pulposus
AF
annulus fibrosus
CEPs
cartilaginous endplates
IDD
intervertebral disc degeneration
ECM
extracellular matrix
miRNAs
microRNAs
RNA pol
RNA polymerase
DGCR8
DiGeorge syndrome critical gene 8
Exp 5
exportin 5
TRBP
transactivating response RNA-binding protein
RISC
RNA-induced silencing complex
Ago
Argonaute
PI3K
phosphoinositide 3-kinase
MAPK
mitogen-activated protein kinase
TGF-β
transforming growth factor-β
PDGF
platelet-derived growth factor
IGF
insulin-like growth factor
EGF
epidermal growth factor
CDKI1B
cyclin-dependent kinase inhibitor 1B
TNF-α
tumor necrosis factor-α
FADD
Fas-associated death domain-containing protein
Col II
type II collagen
Col I
type I collagen
MMPs
matrix metalloproteinases
ADAMTSs
a disintegrin and metalloprotease with thrombospondin motifs
Col I
type I collagen
Col II
type II collagen
FGF2
fibroblast growth factor 2
FGFR
fibroblast growth factor receptor
IL-1β
interleukin-1β
NGF
nerve growth factor
HOXD10
homeobox D10
MiRNAs
IDD
NP cells
Apoptosis
Cell proliferation
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