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科研机构
复旦大学上海医学院 [17]
中南大学 [16]
厦门大学 [11]
上海药物研究所 [9]
山东大学 [9]
西安交通大学 [8]
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期刊论文 [110]
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Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
Hao, Kangwei
;
Xu, Hang
;
Jiang, Shuai
;
Sun, Li
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
The pathogenesis of organ fibrosis: Focus on necroptosis
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2022
作者:
Hao, Min
;
Han, Xin
;
Yao, Zhouhui
;
Zhang, Han
;
Zhao, Mengting
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
liver fibrosis
lung fibrosis
MLKL
necroptosis
RIPK1
3
tissue fibrosis
Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 6
作者:
Yang, Xiangbo
;
Lu, Huimin
;
Xie, Hang
;
Zhang, Binbin
;
Nie, Tianqing
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/01/18
Binding studies
Drug discovery
Necroptosis
RIPK1 inhibitors
Sepsis
Ganoderic acid T improves the radiosensitivity of HeLa cells via converting apoptosis to necroptosis
期刊论文
TOXICOLOGY RESEARCH, 2021, 卷号: 10
作者:
Shao, Chang-Sheng
;
Feng, Na
;
Zhou, Shuai
;
Zheng, Xin-Xin
;
Wang, Peng
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/08/31
ganoderic acid T (GAT)
triterpene
apoptosis
necroptosis
radiosensitivity
ionizing radiation
RIPK1 inhibitor ameliorates colitis by directly maintaining intestinal barrier homeostasis and regulating following IECs-immuno crosstalk
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 172, 页码: 16
作者:
Lu, Huimin
;
Li, Heng
;
Fan, Chen
;
Qi, Qing
;
Yan, Yuxi
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
RIPK1 inhibitor
Colitis
Barrier homeostasis
IECs-immunocytes crosstalk
Necroptosis
NF-kappa B
Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors
期刊论文
TOXICOLOGY LETTERS, 2019, 卷号: 313
作者:
Li, Xiaoqing
;
Peng, Zhao
;
Zhou, Yiling
;
Wang, Jing
;
Lin, Xinyi
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/12/05
Antipsychotics
Quetiapine
Endocannabinoid system
Necroptosis
Cardiotoxicity
EBV(LMP1)-induced metabolic reprogramming inhibits necroptosis through the hypermethylation of the RIP3 promoter
期刊论文
THERANOSTICS, 2019, 卷号: 9, 期号: 9
作者:
Shi, Feng
;
Zhou, Min
;
Shang, Li
;
Du, Qianqian
;
Li, Yueshuo
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/12/05
Epstein-Barr virus
Nasopharyngeal carcinoma
Necroptosis
Receptor-interacting protein 3
Fumarate
The role of necroptosis in cancer biology and therapy
期刊论文
MOLECULAR CANCER, 2019, 卷号: 18
作者:
Gong, Yitao
;
Fan, Zhiyao
;
Luo, Guopei
;
Yang, Chao
;
Huang, Qiuyi
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/05
Necroptosis
Autophagy
Apoptosis
Receptor-interacting protein kinase (RIPK)
Mixed lineage kinase domain-like pseudokinase (MLKL)
Metastasis
Immunosuppression
Therapeutics
The role of necroptosis in cancer: A double-edged sword?
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2019, 卷号: 1871, 期号: 2
作者:
Qin, Xia
;
Ma, Dan
;
Tan, Ye-xiong
;
Wang, Hong-yang
;
Cai, Zhenyu
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Necroptosis
Cancer
Metastasis
RIPK3
MLKL
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