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Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
Cost-effective purification process development for chimeric hepatitis B core (HBc) virus-like particles assisted by molecular dynamic simulation
期刊论文
ENGINEERING IN LIFE SCIENCES, 2021, 页码: 15
作者:
Zhang, Bingyang
;
Yin, Shuang
;
Wang, Yingli
;
Su, Zhiguo
;
Bi, Jingxiu
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  |  
浏览/下载:54/0
  |  
提交时间:2021/08/31
hepatitis B core
molecular dynamic simulation
protein characterization
protein purification
virus‐
like particle
In vitro preparation of uniform and nucleic acid free hepatitis B core particles through an optimized disassembly-purification-reassembly process
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 178, 页码: 7
作者:
Zhang, Yao
;
Liu, Yongdong
;
Zhang, Bingyang
;
Yin, Shuang
;
Li, Xiunan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/08/31
Hepatitis B core (HBc)
Uniform VLPs
Nucleic acid removal
Disassembly-purification-reassembly
A novel rapid modularized hepatitis B core virus-like particle-based platform for personalized cancer vaccine preparation via fixed-point coupling
期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2020, 卷号: 28, 页码: 13
作者:
Ji, Mei
;
Zhu, Jie
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Wang, Bin
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  |  
浏览/下载:18/0
  |  
提交时间:2020/10/30
Hepatitis b Core Protein
Virus-like Particle (Vlp)
Personalized Cancer Vaccine
Spycatcher/spytag
t Cell Epitope
Anti-hepatitis B virus activity of swertisin isolated from Iris tectorum Maxim
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 257, 页码: 9
作者:
Xu, Hong-Yan
;
Ren, Ji-Hua
;
Su, Yu
;
Ren, Fang
;
Zhou, Yu-Jiao
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  |  
浏览/下载:25/0
  |  
提交时间:2020/12/24
Iris tectorum Maxim
Swertisin
Hepatitis B virus
HBsAg
HBeAg
The incorporation of cationic property and immunopotentiator in poly (lactic acid) microparticles promoted the immune response against chronic hepatitis B
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2020, 卷号: 321, 页码: 576-588
作者:
Lu, Ting
;
Hu, Fumin
;
Yue, Hua
;
Yang, Tingyuan
;
Ma, Guanghui
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  |  
浏览/下载:21/0
  |  
提交时间:2020/05/21
Poly (lactic acid) uniform microparticles
Cationic DDAB
STING agonist
Chronic hepatitis B model mice
Therapeutic vaccine
HBc-based virus-like particle assembly from inclusion bodies using 2-methyl-2, 4-pentanediol
期刊论文
PROCESS BIOCHEMISTRY, 2020, 卷号: 89, 页码: 233-237
作者:
Zhang, Yao
;
Yin, Shuang
;
Zhang, Bingyang
;
Bi, Jingxiu
;
Liu, Yongdong
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  |  
浏览/下载:39/0
  |  
提交时间:2020/05/06
Virus-like particle (VLP)
Hepatitis B virus core antigen (HBc)
Inclusion body
Assembly
Sodium dodecyl sulfate (SDS)
2-methyl-2, 4-pentanediol (MPD)
基于疫苗颗粒完整性的硅胶吸附/解吸附纯化重组乙肝表面抗原工艺研究
期刊论文
过程工程学报, 2020, 卷号: 20, 期号: 10, 页码: 1198
作者:
胡胜杰
;
黄永东
;
赵岚
;
朱凯
;
苗壮
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2021/03/29
hepatitis B surface antigen
particle integrity
silica gel adsorption/desorption
response surface methodology
hydrophobic interaction chromatography
乙肝表面抗原
颗粒完整性
硅胶吸附/解吸附
响应面法
疏水层析
Effects of traditional Chinese medicine formula Le-Cao-Shi on hepatitis B: In vivo and in vitro studies
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 244, 页码: 10
作者:
Zhao, Qing
;
Ren, Xia
;
Chen, Min
;
Yue, Shi-Jun
;
Zhang, Meng-Qi
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Formula Le-Cao-Shi
Hepatitis B virus
Anti-Hepatitis B
Treatment of Chronic Hepatitis B Virus Infection Using Small Molecule Modulators of Nucleocapsid Assembly: Recent Advances and Perspectives
期刊论文
ACS INFECTIOUS DISEASES, 2019, 卷号: 5, 期号: 5, 页码: 713-724
作者:
Yang, Li
;
Liu, Feifei
;
Tong, Xiankun
;
Hoffmann, Daniel
;
Zuo, Jianping
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
hepatitis B virus
HBV core protein
HBcAg
capsid assembly
capsid assembly modulators (CAMs)
antiviral therapy
clinical trials
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