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Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin
期刊论文
出版物, 3111, 期号: 0, 页码: 1-62
作者:
M Iijima
;
T Yoshimizu
;
T Shimazaki
;
K Tokugawa
;
K Fukumoto
收藏
  |  
浏览/下载:581/0
  |  
提交时间:2017/07/24
Arginine Vasopressin
V1b Receptor Antagonist
Depression
Anxiety
Hpa Axis
Linalool: A ubiquitous floral volatile mediating the communication between plants and insects
期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2023, 卷号: 61, 期号: 3, 页码: 538-549
作者:
Zhang, Ling
;
Su, Qia-Fan
;
Wang, Liang-Sheng
;
Lv, Meng-Wen
;
Hou, Yi-Xuan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/07
antagonist
floral volatiles
linalool
plant-insect interactions
pollination
Discovery of 1,5-Dihydro-4H-imidazol-4-one Derivatives as Potent, Selective Antagonists of CXC Chemokine Receptor 2
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 5, 页码: 836-845
作者:
Che, Jinxin
;
Wang, Zhilong
;
Shen, Zheyuan
;
Zhuang, Weihao
;
Ying, Huazhou
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/08/17
cancer metastasis
CXCR1
CXCR2
selectivity
antagonist
1,5-dihydro-4H-imidazol-4-one
Medulloblastoma: Molecular understanding, treatment evolution, and new developments
期刊论文
PHARMACOLOGY & THERAPEUTICS, 2020, 卷号: 210, 页码: 13
作者:
Liu, Xiaohua
;
Ding, Chunyong
;
Tan, Wenfu
;
Zhang, Ao
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Medulloblastoma
Pediatric brain tumor
Oncogenic driver gene
Hedgehog pathway inhibitor
Smoothened receptor antagonist
Revealing the Positive Binding Cooperativity Mechanism between the Orthosteric and the Allosteric Antagonists of CCR2 by Metadynamics and Gaussian Accelerated Molecular Dynamics Simulations
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 4, 页码: 628-637
作者:
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Liu, Hongli
;
Zhang, Qianqian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/18
CC chemokine receptor 2
orthosteric antagonist
allosteric antagonist
binding cooperativity
metadynamics simulation
Gaussian accelerated MD simulation
Systematic characterization of AT1 receptor antagonists with label-free dynamic mass redistribution assays
期刊论文
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2020, 卷号: 102
作者:
Qu, Lala
;
Wang, Jixia
;
Hou, Tao
;
Zhou, Han
;
Wang, Zhiwei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/11/25
Angiotensin II type 1 receptor
Antagonist
Binding property
Dynamic mass redistribution assay
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
收藏
  |  
浏览/下载:265/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
How Does Agonist and Antagonist Binding Lead to Different Conformational Ensemble Equilibria of the kappa-Opioid Receptor: Insight from Long-Time Gaussian Accelerated Molecular Dynamics Simulation
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 3, 页码: 1575-1584
作者:
An, Xiaoli
;
Bai, Qifeng
;
Bing, Zhitong
;
Zhou, Shuangyan
;
Shi, Danfeng
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/11/10
kappa-opioid receptor
Gaussian accelerated molecular dynamics simulation
agonist
antagonist
conformational change
Aclidinium Bromide holds promising inhibitory effects in A549 lung cancer cells potentials by regulating PI3K/AKT signaling pathway
期刊论文
JOURNAL OF BUON, 2019, 卷号: 24, 期号: 2
作者:
Shi, Dan
;
Liu, Tao
;
Lin, Gang
;
Guan, Wei
;
Cheng, Guanghui
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/05
Aclidinium Bromide
muscarinic antagonist
lung cancer
proliferation
migration
PI3K/Akt
The IAP antagonist birinapant potentiates bortezomib anti-myeloma activity in vitro and in vivo
期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 卷号: 12
作者:
Zhou, Liang
;
Zhang, Yu
;
Leng, Yun
;
Dai, Yun
;
Kmieciak, Maciej
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/12/05
Multiple myeloma
IAP antagonist
Bortezomib
NF-B
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