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Spy1, a unique cell cycle regulator, alters viability in ALS motor neurons and cell lines in response to mutant SOD1-induced DNA damage 期刊论文
DNA REPAIR, 2019, 卷号: 74
作者:  Qi, Yan;  Wang, Xu-Dong;  Zhu, Min-Wei;  Shan, Dan;  Wang, Shu-Yu
收藏  |  浏览/下载:29/0  |  提交时间:2019/12/05
Characteristics of the Copper,Zinc Superoxide Dismutase of a Hadal Sea Cucumber (Paelopatides sp.) from the Mariana Trench 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 5, 页码: 1
作者:  Liu, Helu;  Zhang, Haibin;  Li, Yanan;  Kong, Xue;  Chen, Jiawei
收藏  |  浏览/下载:33/0  |  提交时间:2018/06/22
Live or let die: Neuroprotective and anti-cancer effects of nutraceutical antioxidants 期刊论文
Pharmacology and Therapeutics, 2018, 卷号: 183, 页码: 137-151
作者:  Mao, Xiao-Yuan*;  Jin, Ming-Zhu;  Chen, Jin-Fei*;  Zhou, Hong-Hao;  Jin, Wei-Lin*
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/03
PD  Parkinson's disease  AD  Alzheimer's disease  EGCG  (−)-Epigallocatechin-3-gallate  NRF2  NF-E2-related factor 2  ROS  reactive oxygen species  H2O2  hydrogen peroxide  ER  endoplasmic reticulum  GPX  glutathione-peroxidase  NOX  NADPH oxidases (NOXs)  LOX  lipoxygenases  ERK  extracellular signal-regulated kinase  JNK  c-Jun amino-terminal kinase  MAPK  mitogen-activated protein kinase  HNE  4-hydroxy-2-nonenol  ARE  antioxidant responsive element  GST  glutathione S-transferase  IFNγ  interferon-γ  LPS  lipopolysaccharide  SOD  superoxide dismutase  TNF-α  tumor necrosis factor-α  APP  β-amyloid precursor protein  SAM  S-adenosylmethionine  MAT  methionine adenosyltransferase  SAH  Sadenosyl homocysteine  MT  methyltransferases  BDNF  brain-derived neurotrophic factor  Nutraceuticals  Neuroprotection  Anti-cancer  ROS addiction  Ferroptosis  Oxidative stress  
Selective binding, magnetic separation and purification of histidine-tagged protein using biopolymer magnetic core-shell nanoparticles 期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2018, 卷号: Vol.144, 页码: 5-11
作者:  Zhou,Yang;  Fletcher,Emmanuella E.;  Shi,Haifeng;  Yan,Dandan;  Han,Bangxing
收藏  |  浏览/下载:5/0  |  提交时间:2019/04/22
Effects of over-expression of SOD2 in bone marrow-derived mesenchymal stem cells on traumatic brain injury 期刊论文
CELL AND TISSUE RESEARCH, 2018, 卷号: 372, 期号: 1, 页码: 67-75
作者:  Shi, Xiaodong;  Bai, Yunan;  Zhang, Guodong;  Liu, Yuguang;  Xiao, Hang
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/11
Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice 期刊论文
Journal of Functional Foods, 2018, 卷号: 44, 页码: 155-165
作者:  Li, Xiaopeng;  Wu, Qian;  Sui, Yong;  Li, Shuyi;  Xie, Bijun
收藏  |  浏览/下载:48/0  |  提交时间:2019/12/27
A-type procyanidins  Oxidative stress  Glucose homeostasis  Type 2 diabetes  mTOR  ACC1  acetyl coenzyme A carboxylase 1  ACL  ATP-citrate lyase  ALT  alanine aminotransferase  AST  aspartate aminotransferase  AUC  area under curve  BAT  brown adipose tissue  FAS  fatty acid synthase  FFA  free fatty acid  FoxO3a  Forkhead box O3a  FoxO1a  Forkhead box O3a  PKCβ  protein kinase C β  mTOR  mechanistic target of rapamycin  HDL  high-density lipoprotein  GHbA1c  glycated hemoglobin A1c  GK  glucokinase  G-6-Pase  glucose-6-phosphatase  GLP-1  glucagon-like peptide-1  GSH-PX  total glutathione peroxidase  HOMA-IR  homeostatic model assessment of insulin resistance  LDHA  lactate dehydrogenase  LDL  low-density lipoprotein  LPOPC  oligomeric procyanidins of litchi pericarp  MDA  malondialdehyde  MnSOD  manganese superoxide dismutase  mTOR  mechanistic target of rapamycin  OGTT  oral glucose tolerance test  PDH  pyruvate dehydrogenase  PEPCK  phosphoenolpyruvate carboxykinase  PFK  phosphofructokinase  PK  pyruvate kinase  PKCβ  protein kinase C β  PPG  postprandial blood glucose  S6K1  S6 Kinase 1  PKCβ  protein kinase C β  RTK  receptor tyrosine kinase  SREBP-1c  sterol regulatory element-binding protein 1c  ACL  ATP-citrate lyase  ACC1  acetyl coenzyme A carboxylase 1  FAS  fatty acid synthase  SCD1  stearoyl CoA desaturase 1  STZ  streptozotocin  S6K1  S6 kinase 1  PPG  postprandial blood glucose  ROS  reactive oxygen species  TC  total cholesterol  TG  triacylglycerol  STZ  streptozotocin  T-AOC  total antioxidant capacity  T-SOD  total superoxide dismutase  UCP-1  uncoupling protein 1  WAT  white adipose tissue  XOS  xylo-oligosaccharides  
Aucubin and its hydrolytic derivative attenuate activation of hepatic stellate cells via modulation of TGF-β stimulation 期刊论文
Environmental Toxicology and Pharmacology, 2017, 卷号: 50, 页码: 234-239
作者:  Lv, Pei-Yu;  Feng, Han;  Huang, Wei-Hua;  Tian, Ying-Ying;  Wang, Ya-Qin
收藏  |  浏览/下载:1/0  |  提交时间:2019/12/03
Combination of metformin with chemotherapeutic drugs via different molecular mechanisms 期刊论文
Cancer Treatment Reviews, 2017, 卷号: 54, 页码: 24-33
作者:  Peng, Mei*;  Darko, Kwame Oteng;  Tao, Ting;  Huang, Yanjun;  Su, Qiongli
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/03
AIs  aromatase inhibitors  AMPK  Adenosine Monophosphate-Activated Protein Kinase  AR  androgen  ATM  Ataxia Telangiectasia Mutated  ATP  Adenosine Triphosphate  BCSS  breast cancer specific survival  CK-MB  Creatine Kinase-MB  CREB1  cAMP Response Element-Binding Protein 1  CSC  cancer stem cell  DFS  disease-free survival  DHFU  dihydrofluorouracil  DPD  dihydropyrimidine dehydrogenase  EpCAM  Epithelial Cell Adhesion Molecule  ER  estrogen  ERCC1  excision repair cross-complementary 1  ERK  extracellular signal-regulated kinases  EZH2  enhancer of zeste homolog 2  FdUMP  fluorodeoxyuridine monophosphate  FdUTP  fluorodeoxyuridine triphosphate  FHC  ferritin heavy chain  FUTP  fluorouridine triphosphate  HbA1C  hemoglobin A1c  HER  Human Epidermal Growth Factor Receptor  HIF-1α  hypoxia-inducible factor-1α  HK  hexokinase  IGF1R  insulin growth factor 1 receptor  LDH  lactate dehydrogenase  MDA  Muscular Dystrophy Association  MMP  Matrix Metallopeptidase  MRP1  multidrug resistance-associated protein 1  mTOR  mammalian target of rapamycin  MTX  methotrexate  NCCN  National Comprehensive Cancer Network  OS  overall survival  pCR  Pathologic Complete Response  PDGFR  platelet-derived growth factor receptors  PFS  progression-free survival  PKA  protein kinase A  PR  progesterone receptor  RFS  relapse-free survival  SOD  superoxide dismutase  TAM  tamoxifen  TCA  tricarboxlic acid  TS  thymidylate synthase  Combination  Mechanisms  Metformin  Chemotherapeutic drugs  
Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila 期刊论文
Brain Research Bulletin, 2017, 卷号: 132, 页码: 222-231
作者:  Jiang, Ming-Di;  Zheng, Ya;  Wang, Jia-Lin;  Wang, Yu-Feng*
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/23
不同蛋白源饲料中添加 α-酮戊二酸对松浦镜鲤抗氧化能力的影响 期刊论文
水产学杂志, 2017, 卷号: 30, 期号: 5, 页码: 28-32
作者:  李晋南[1];  徐奇友[2];  魏玉强[3]
收藏  |  浏览/下载:5/0  |  提交时间:2020/01/02


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