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科研机构
上海药物研究所 [8]
厦门大学 [3]
西安交通大学 [3]
中南大学 [3]
复旦大学上海医学院 [2]
南华大学 [1]
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期刊论文 [32]
发表日期
2019 [2]
2018 [3]
2017 [4]
2016 [2]
2015 [3]
2014 [4]
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Synthesis and Biological Evaluation of Five-Atom-Linker-Based Arylpiperazine Derivatives with an Atypical Antipsychotic Profile
期刊论文
CHEMMEDCHEM, 2019, 页码: 11
作者:
Wu, Chunhui
;
Wang, Yu
;
Yang, Feipu
;
Shi, Wenqiang
;
Wang, Zhen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
D-2
5-HT1A
5-HT2A
serotonin
SERT
PCP-induced hyperactivity
Dysfunction in Serotonergic and Noradrenergic Systems and Somatic Symptoms in Psychiatric Disorders.
期刊论文
FRONTIERS IN PSYCHIATRY, 2019, 卷号: 10, 期号: MAY, 页码: 286
作者:
Liu, Yi
;
Zhao, Jingping
;
Fan, Xiaoduo
;
Guo, Wenbin*
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/03
mono-aminergic neurotransmitters
norepinephrine (NE)
pathophysiology
serotonin (5-HT)
somatic symptoms
Co-activation of both 5-HT1A and 5-HT7 receptors induced attenuation of glutamatergic synaptic transmission in the rat visual cortex.
期刊论文
Neuroscience letters, 2018, 卷号: 686, 页码: 122-126
作者:
Li Yan-Hai
;
Xiang Kangjian
;
Xu Xingzhe
;
Zhao Xuefei
;
Li Youjun
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/19
AMPA receptor
Serotonin
5-HT(7) receptor
Visual cortex
5-HT(1A) receptor
Electroacupuncture restores hippocampal synaptic plasticity via modulation of 5-HT receptors in a rat model of depression
期刊论文
BRAIN RESEARCH BULLETIN, 2018, 卷号: 139
作者:
Lao, Lixing
;
Han, Xuke
;
Wu, Huangan
;
Yin, Ping
;
Chen, Zeqin
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Electroacupuncture (EA)
Serotonin (5-HT)
Long-term potentiation (LTP)
Depression
Electroacupuncture restores hippocampal synaptic plasticity via modulation of 5-HT receptors in a rat model of depression
期刊论文
Brain research bulletin, 2018, 卷号: 139, 页码: 256-262
作者:
Han Xuke[1]
;
Wu Huangan[2]
;
Yin Ping[3]
;
Chen Zeqin[4]
;
Cao Xiaohua[5]
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/04/24
Depression
Electroacupuncture (EA)
Long-term potentiation (LTP)
Serotonin (5-HT)
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:
Xiamuxi, Hainimu
;
Wang, Zhen
;
Li, Jianfeng
;
Wang, Yu
;
Wu, Chunhui
收藏
  |  
浏览/下载:121/0
  |  
提交时间:2019/01/08
Dopamine
Serotonin
Multireceptor
Atypical antipsychotic
5-HT1A
Synthesis and biological investigation of tetrahydropyridopyrimidinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4904-4916
作者:
Xiamuxi, H (Xiamuxi, Hainimu)
;
Wang, Z (Wang, Zhen)
;
Li, JF (Li, Jianfeng)
;
Wang, Y (Wang, Yu)
;
Wu, CH (Wu, Chunhui)
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2017/10/31
Dopamine
Serotonin
Multireceptor
Atypical Antipsychotic
5-ht1a
Drug induces depression-like phenotypes and alters gene expression profiles in Drosophila
期刊论文
Brain Research Bulletin, 2017, 卷号: 132, 页码: 222-231
作者:
Jiang, Ming-Di
;
Zheng, Ya
;
Wang, Jia-Lin
;
Wang, Yu-Feng*
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/23
5-HT
serotonin
BP
biological process
CC
cellular component
Con
control flies
CPZ
flies fed with 2000 mg/L of Chlorpromazine for 48 h
DEGs
differentially expressed genes
dscDNA
double-strand cDNA
FXS
Fragile X syndrome
GO
Gene ontology
IL
interleukin
MDA
malondialdehyde
MDD
major depressive disorder
MF
molecular function
qRT-PCR
quantitative reverse transcriptase PCR
SOD
superoxide dismutase
Drosophila melanogaster
Depression
Chlorpromazine
RNA-Seq
Differentially expressed genes
Apelin/APJ system: A bifunctional target for cardiac hypertrophy
期刊论文
International Journal of Cardiology, 2017, 卷号: 230, 页码: 164-170
作者:
Lu, Liqun
;
Wu, Di
;
Li, Lanfang*
;
Chen, Linxi*(陈临溪)
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Apelin/APJ system
Cardiac hypertrophy
Oxidative stress
Obesity
Hypertension
Myocardial infarction
AT1R
angiotensin II type 1 receptor
Ang II
angiotensin II
PCSK3
proprotein convertase subtilisin/kexin3
5-HT
serotonin
TNF-α
tumor necrosis factor-a
HW/BW
the ratio of heart weight/body weight
ANP
atrial natriuretic peptide
LV
left ventricular
ANF
atrial natriuretic factor
TGF-β1
transforming growth factor beta1
ROS
reactive oxygen species
β-MHC
beta-myosin heavy chain
HFD
high-fat diet
ER
endoplasmic reticulum
FA
fatty acid
MI
myocardial infarction
ACE2
angiotensin-converting enzyme 2
LVH
left ventricular hypertrophy
Selective 5-HT7 Receptor Activation May Enhance Synaptic Plasticity Through N-methyl-D-aspartate (NMDA) Receptor Activity in the Visual Cortex
期刊论文
CURRENT NEUROVASCULAR RESEARCH, 2016, 卷号: 13, 期号: [db:dc_citation_issue], 页码: 321-328
作者:
Xiang, Kangjian
;
Zhao, Xuefei
;
Li, Youjun
;
Zheng, Liang
;
Wang, Jue
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/02
Serotonin
5-HT7 receptor
visual cortex
mEPSCs
NMDA receptor
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