QQ客服 官方微博 反馈留言

浏览/检索结果: 共3条，第1-3条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020) 期刊论文 CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842 作者:  Wu, Jingwei;  Zhang, Huan;  Zhao, Guilong;  Wang, Runling 收藏  |  浏览/下载：65/0  |  提交时间：2021/08/17 SHP2 inhibitor  PTPN11 gene  allosteric  cancer  combination therapy  clinical trial   Microduplication of 3p25.2 encompassing RAF1 associated with congenital heart disease suggestive of Noonan syndrome 期刊论文 American Journal of Medical Genetics Part A, 2012, 卷号: 158A, 期号: 8, 页码: 1918-1923 作者:  Luo, Cheng;  Yang, Yi-Feng;  Yin, Bang-Liang;  Chen, Jin-Lan;  Huang, Can 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/03 Noonan syndrome  Noonan syndrome with multiple lentigines  RAF1  PTPN11  duplication 3p25.2  SNP array  dosage sensitive gene  copy number variation  CNV  congenital heart defect   Deletion of Shp2 Tyrosine Phosphatase in Muscle Leads to Dilated Cardiomyopathy, Insulin Resistance, and Premature Death 期刊论文 http://dx.doi.org/10.1128/MCB.01661-08, 2009 Princen, Frederic; Bard, Emilie; Sheikh, Farah; Zhang, Sharon S.; Wang, Jing; Zago, Wagner M.; Wu, Dongmei; Trelles, Ramon Diaz; Bailly-Maitre, Beatrice; Kahn, C. Ronald; Chen, Yan; Reed, John C.; Tong, Gary G.; Mercola, Mark; Chen, Ju; Feng, Gen-Sheng; 王军 收藏  |  浏览/下载：4/0  |  提交时间：2013/12/12 ACTIVATED PROTEIN-KINASE  HEART-FAILURE  CARDIAC-HYPERTROPHY  SIGNALING PATHWAYS  RECEPTOR SUBSTRATE-1  GENE-EXPRESSION  PTPN11 SHP2  CARDIOMYOCYTES  MOUSE  MECHANISM