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浏览/检索结果: 共4条，第1-4条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Molecular insight into the T798M gatekeeper mutation-caused acquired resistance to tyrosine kinase inhibitors in ErbB2-positive breast cancer 期刊论文 COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78 作者:  Lu, Ji;  Zhou, Kun;  Yin, Xiaoxing;  Xu, Han;  Ma, Baojin 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/05 Epidermal growth factor receptor 2  Gatekeeper mutation  Tyrosine kinase inhibitor  Acquired resistance  Breast cancer   Revisiting the molecular mechanism of acquired resistance to reversible tyrosine kinase inhibitors caused by EGFR gatekeeper T790M mutation in non-small-cell lung cancer 期刊论文 MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 9, 页码: 2160-2170 作者:  Zhao, Yan;  Jiao, Yingjie;  Sun, Fengzhe;  Liu, Xudong 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 Epidermal growth factor receptor  Gatekeeper T790M mutation  Tyrosine  kinase inhibitor  Acquired resistance  Non-small-cell lung cancer   Integrated Exploitation of the Structural Diversity Space of Chemotherapy Drugs to Selectively Inhibit HER2 T798M Mutant in Lung Cancer 期刊论文 CHEMISTRY & BIODIVERSITY, 2017, 卷号: 14, 期号: 3 作者:  Wang, Ya-Wei;  Zhang, Hai-Yan;  Li, Ji-Sheng;  Wang, Xiu-Wen 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11 Human epidermal growth factor receptor 2  T798M Gatekeeper mutation  Structural diversity  Chemical space  Lung cancer  Chemotherapy drug   Design, synthesis and pharmacological evaluation of 2-(thiazol-2-amino)-4-arylaminopyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 86, 页码: 438-448 作者:  Liu, Zhiqing;  Yue, Xihua;  Song, Zilan;  Peng, Xia;  Guo, Junfeng 收藏  |  浏览/下载：58/0  |  提交时间：2019/01/08 2-Aminothiazole  ALK kinase  Gatekeeper mutation  2,4-Diarylaminopyrimidine  Non-small-cell lung cancer