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上海大学 [4]
上海神经科学研究所 [3]
中南大学 [3]
北京大学 [2]
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中国科学院大学 [2]
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期刊论文 [27]
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Understanding Genotypes and Phenotypes of the Mutations in Voltage-Gated Sodium Channel alpha Subunits in Epilepsy
期刊论文
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 2019, 卷号: 18, 期号: 4
作者:
Feng, Yijun
;
Zhang, Shuzhang
;
Zhang, Zhiping
;
Guo, Jingkang
;
Tan, Zhiyong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/05
Voltage-gated sodium channels
alpha subunits
mutation
epilepsy
seizures
pathophysiological
Modulatory effects of bufalin, an active ingredient from toad venom on voltage-gated sodium channels
期刊论文
MOLECULAR BIOLOGY REPORTS, 2018, 卷号: 45, 期号: 5
作者:
Tao, Jie
;
Jiang, Feng
;
Liu, Cheng
;
Liu, Zhirui
;
Zhu, Yudan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
Voltage-gated sodium channels
Bufalin
Dose dependent inhibition
Anti-nociceptive effects
ND7-23 cell
Understanding Genotypes and Phenotypes of Voltage-Gated Sodium Channel Mutations in Epilepsy
期刊论文
CNS & neurological disorders drug targets, 2018
作者:
Zhang Shuzhang[1]
;
Zhu Yudan[2]
;
Zhang Zhiping[3]
;
Tao Jie[4]
;
Ji Yonghua[5]
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/04/22
epilepsy.
mutation
voltage-gated sodium channels
Nav beta 2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing
期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 59
作者:
Zhang, Lian-Feng
;
Hu, Tao
;
Xiao, Zhangang
;
Mao, Rui
;
Chen, Bo
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/12/04
voltage-gated sodium channels beta 2
Alzheimer's disease
APP/PS1 mouse
neuronal activity
cognition
Gerotarget
Transient upregulation of Nav1.6 expression in the genu of corpus callosum following middle cerebral artery occlusion in the rats
期刊论文
BRAIN RESEARCH BULLETIN, 2017, 卷号: 132
作者:
Zhu, Hongyan
;
Lin, Weide
;
Zhao, Yuxiao
;
Wang, Ziyi
;
Lao, Wenwen
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Ischemia
Voltage-gated sodium channels
Nav1.6
Astrocytes
The genu of corpus callosum
Transient upregulation of Nav1.6 expression in the genu of corpus callosum following middle cerebral artery occlusion in the rats
期刊论文
BRAIN RESEARCH BULLETIN, 2017, 卷号: 132, 页码: 20-27
作者:
Zhu, Hongyan[1]
;
Lin, Weide[2]
;
Zhao, Yuxiao[3]
;
Wang, Ziyi[4]
;
Lao, Wenwen[5]
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/04/24
Ischemia
Voltage-gated sodium channels
Nav1.6
Astrocytes
The genu of corpus callosum
The nonproton ligand of acid-sensing ion channel 3 activates mollusk-specific FaNaC channels via a mechanism independent of the native FMRFamide peptide
期刊论文
Journal of Biological Chemistry, 2017, 卷号: 292, 期号: 52, 页码: 21662-21675
作者:
Yang, Xiao-Na
;
Niu, You-Ya
;
Liu, Yan
;
Yang, Yang
;
Wang, Jin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/23
*2-guanidine-4-methylquinazoline (GMQ)
*FMRFamide (Phe-Met-Arg-Phe-NH2) peptides
*FMRFamide peptide-gated sodium channel (FaNaC)
*acid-sensing ion channels (ASIC)
*epithelial sodium channel (ENaC)
*ion channel
*ligand-binding protein
*neuropeptide
*small molecule
Nav beta 2 knockdown improves cognition in APP/PS1 mice by partially inhibiting seizures and APP amyloid processing
期刊论文
2017, 卷号: 8, 期号: 59, 页码: 99284-99295
作者:
Hu, Tao
;
Xiao, Zhangang
;
Mao, Rui
;
Chen, Bo
;
Lu, Min-Nan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/01/04
voltage-gated sodium channels beta 2
Alzheimer's disease
APP/PS1 mouse
neuronal activity
cognition
Gerotarget
Molecular determinant for the tarantula toxin Jingzhaotoxin-I slowing the fast inactivation of voltage-gated sodium channels
期刊论文
Toxicon, 2016, 卷号: 111, 期号: Volume 111, 页码: 13-21
作者:
Tao, Huai*
;
Chen, Xia
;
Lu, Min
;
Wu, Yuanyuan
;
Deng, Meichun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
Jingzhaotoxin-I
Voltage-gated sodium channels
Inactivation
Mutation
JZTX
Jingzhaotoxin
VGSCs
voltage-gated sodium channels
TTX
tetrodotoxin
ICK
inhibitor cystine knot
RP-HPLC
reverse-phase high pressure liquid chromatography
MALDI-TOF
matrix assisted laser desorption/ionization time-of-flight
IC50
half-maximal inhibitory concentration
WT
wide type
FGF13 modulates the gating properties of the cardiac sodium channel Na(v)1.5 in an isoform-specific manner
期刊论文
CHANNELS, 2016, 卷号: 10, 期号: 5, 页码: 410-420
作者:
Yang, Jing
;
Wang, Zhihua
;
Sinden, Daniel S.
;
Wang, Xiangchong
;
Shan, Bin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/16
activation
fibroblast growth factor homologous factors
FGF13
gating
inactivation
isoform
Nav1
5
N-termini
recovery from inactivation
voltage gated sodium channels
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