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北京大学 [6]

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	TALEN-Mediated Knockout of CCR5 Confers Protection Against Infection of Human Immunodeficiency Virus 期刊论文 JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 2017 Shi, Bingjie; Li, Juan; Shi, Xuanling; Jia, Wenxu; Wen, Yi; Hu, Xiongbing; Zhuang, Fengfeng; Xi, Jianzhong; Zhang, Linqi 收藏 \| 浏览/下载：3/0 \| 提交时间：2017/12/03 HIV-1 CCR5 genome editing TALEN and ZFN ZINC-FINGER NUCLEASES DEFICIENCY-SYNDROME AIDS OFF-TARGET CLEAVAGE CD4(+) T-CELLS HIV-1 INFECTION DISEASE PROGRESSION CORECEPTOR USAGE IN-VIVO EFFECTOR NUCLEASES HEMATOPOIETIC STEM
	Precise Genome Modification via Sequence-Specific Nucleases-Mediated Gene Targeting for Crop Improvement 期刊论文 FRONTIERS IN PLANT SCIENCE, 2016, 卷号: 7, 页码: - 作者: Sun, Yongwei; Li, Jingying; Xia, Lanqin 收藏 \| 浏览/下载：5/0 \| 提交时间：2017/05/03 clustered regularly interspersed short palindromic repeats (CRISPR)/Cas9 crops double strand breaks (DSBs) gene targeting (GT) homology-directed repair (HDR) sequence-specific nucleases (SSNs) transcription activator-like effector nucleases (TALENs) zinc finger nucleases (ZFNs)
	TALENs-Assisted Multiplex Editing for Accelerated Genome Evolution To Improve Yeast Phenotypes 期刊论文 ACS SYNTHETIC BIOLOGY, 2015, 卷号: 4, 期号: 10, 页码: 1101-1111 作者: Zhang, Guoqiang; Lin, Yuping; Qi, Xianni; Li, Lin; Wang, Qinhong 收藏 \| 浏览/下载：17/0 \| 提交时间：2016/06/23 transcription activator-like effector nucleases multiplex editing genome evolution cellular phenotypes
	The application of genome editing in studying hearing loss 期刊论文 Hearing Research, 2015, 卷号: 327, 期号: Volume 327, 页码: 102-108 作者: Zou, Bing; Mittal, Rahul; Grati, M'hamed; Lu, Zhongmin; Shu, Yilai 收藏 \| 浏览/下载：9/0 \| 提交时间：2019/12/03 AAV Adeno-associated virus ARHL age-related hearing loss Cas9 CRISPR-associated nuclease 9 CRISPR clustered, regularly interspaced, short palindromic repeat crRNA CRISPR RNA dCas9 defective Cas9 DSBs double-strand breaks gRNA guide RNA HDR homology-directed-repair HL hearing loss HR homologous recombination NHEJ non-homologous-end-joining PAM protospacer-adjacent motif RVD repeat-variable di-residue siRNA small interfering RNA TALENs transcriptional activator-like effector nucleases TALEs transcription activator-like effectors tracrRNA trans-acting crRNA ZFNs Zinc finger nucleases
	Efficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs 期刊论文 scientific reports, 2014 Yao, Jing; Huang, Jiaojiao; Hai, Tang; Wang, Xianlong; Qin, Guosong; Zhang, Hongyong; Wu, Rong; Cao, Chunwei; Xi, Jianzhong Jeff; Yuan, Zengqiang; Zhao, Jianguo 收藏 \| 浏览/下载：9/0 \| 提交时间：2015/11/11 ZINC-FINGER NUCLEASES FIBROBLAST-GROWTH-FACTOR PARKIN-DEFICIENT MICE EMBRYO MICROINJECTION NULL MICE EFFECTOR NUCLEASES TARGETING DNA GENERATION MUTATIONS DISEASE
	Mutagenesis at Specific Genomic Loci of Amphioxus Branchiostoma belcheri Using TALEN Method 期刊论文 http://dx.doi.org/10.1016/j.jgg.2014.02.003, 2014 Li, Guang; Feng, Jun; Lei, Yong; Wang, Jing; Wang, Hui; Shang, Liu-Ke; Liu, Dong-Teng; Zhao, Hui; Zhu, Yong; Wang, Yi-Quan; 李光; 王义权收藏 \| 浏览/下载：3/0 \| 提交时间：2015/07/22 CHROMOSOMAL DELETIONS DEVELOPMENTAL BIOLOGY EFFECTOR NUCLEASES HIGH-EFFICIENCY ZEBRAFISH CRISPR/CAS INVERSIONS
	Inheritable and Precise Large Genomic Deletions of Non-Coding RNA Genes in Zebrafish Using TALENs 期刊论文 PLOS ONE, 2013, 卷号: 8, 期号: 10, 页码: e76387 作者: Liu, Yun; Luo, Daji; Zhao, Hui; Zhu, Zuoyan; Hu, Wei 收藏 \| 浏览/下载：20/0 \| 提交时间：2014/01/06 ZINC-FINGER NUCLEASES EFFECTOR NUCLEASES CHROMOSOMAL DELETIONS EMBRYONIC-DEVELOPMENT MICRORNA EXPRESSION TRANSCRIPTION CELLS KNOCKOUT ORGANIZATION RECOGNITION
	TALEN or Cas9-Rapid, Efficient and Specific Choices for Genome Modifications 期刊论文遗传学报, 2013 Wei, Chuanxian; Liu, Jiyong; Yu, Zhongsheng; Zhang, Bo; Gao, Guanjun; Jiao, Renjie 收藏 \| 浏览/下载：4/0 \| 提交时间：2015/11/11 Genome editing TALEN CRISPR/Cas9 Gene therapy Stem cells ZINC-FINGER NUCLEASES EFFECTOR NUCLEASES GENE-EXPRESSION IN-VIVO DROSOPHILA GENOME STRUCTURAL BASIS DNA RECOGNITION IMMUNE-SYSTEM III EFFECTORS TARGET SITES
	Crystal structure of a TALE protein reveals an extended N-terminal DNA binding region 期刊论文细胞研究英文版, 2012 Gao, Haishan; Wu, Xiaojing; Chai, Jijie; Han, Zhifu 收藏 \| 浏览/下载：2/0 \| 提交时间：2015/11/16 DOUBLE-STRAND BREAKS EFFECTOR NUCLEASES III EFFECTORS TRANSCRIPTION SPECIFICITY RECOGNITION
	Reverse Genetic Approaches in Zebrafish 期刊论文遗传学报, 2012 Huang, Peng; Zhu, Zuoyan; Lin, Shuo; Zhang, Bo 收藏 \| 浏览/下载：3/0 \| 提交时间：2015/11/10 Zebrafish Reverse genetics Morpholino TILLING Retrovirus ZFN TALEN Gene targeting ZINC-FINGER NUCLEASES MORPHOLINO ANTISENSE OLIGOMERS DNA-BINDING SPECIFICITY TAL EFFECTOR NUCLEASES MEDIATED ENHANCER TRAP DOUBLE-STRAND BREAKS IN-VIVO INSERTIONAL MUTAGENESIS VERTEBRATE DEVELOPMENT EMBRYO MICROINJECTION

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