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CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4 期刊论文
CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 5, 页码: 651, 669
作者:  Chen, C;  Chu, SF;  Ai, QD
收藏  |  浏览/下载:78/0  |  提交时间:2019/06/14
IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization. 期刊论文
International immunopharmacology, 2019, 卷号: Vol.70, 页码: 69-79
作者:  Chen Chen;  Qidi Ai;  Shifeng Chu;  Zhao Zhang;  Xin Zhou
收藏  |  浏览/下载:19/0  |  提交时间:2019/12/13
IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization 期刊论文
International Immunopharmacology, 2019, 卷号: Vol.70, 页码: 69-79
作者:  Chen Chen;  Qidi Ai;  Shifeng Chu;  Zhao Zhang;  Xin Zhou
收藏  |  浏览/下载:20/0  |  提交时间:2019/12/13
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文
2019, 卷号: 212, 页码: 36-53
作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun
收藏  |  浏览/下载:26/0  |  提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator  
IMM-H004 Protects against Cerebral Ischemia Injury and Cardiopulmonary Complications via CKLF1 Mediated Inflammation Pathway in Adult and Aged Rats 期刊论文
2019, 卷号: 20, 期号: 7
作者:  Ai, Qidi;  Chen, Chen;  Chu, Shifeng;  Luo, Yun;  Zhang, Zhao
收藏  |  浏览/下载:7/0  |  提交时间:2020/01/03
CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4 期刊论文
2019, 卷号: 39, 期号: 5, 页码: 651-669
作者:  Chen, Chen;  Chu, Shi-Feng;  Ai, Qi-Di;  Zhang, Zhao;  Guan, Fei-Fei
收藏  |  浏览/下载:5/0  |  提交时间:2020/01/03
IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization 期刊论文
2019, 卷号: 70, 页码: 69-79
作者:  Chen, Chen;  Ai, Qidi;  Chu, Shifeng;  Zhang, Zhao;  Zhou, Xin
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/03
IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization. 期刊论文
International immunopharmacology, 2019, 卷号: 70, 页码: 69-79
作者:  Chen, Chen;  Ai, Qidi;  Chu, Shifeng;  Zhang, Zhao;  Zhou, Xin
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/27
IMM-H004 Protects against Cerebral Ischemia Injury and Cardiopulmonary Complications via CKLF1 Mediated Inflammation Pathway in Adult and Aged Rats. 期刊论文
International journal of molecular sciences, 2019, 卷号: 20, 期号: 7
作者:  Ai, Qidi;  Chen, Chen;  Chu, Shifeng;  Luo, Yun;  Zhang, Zhao
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/27
IMM-H004 therapy for permanent focal ischemic cerebral injury and cardiopulmonary complications via CKLF1/CCR4-mediated inflammation pathway 期刊论文
Chinese Journal of Pharmacology and Toxicology, 2018, 期号: 9, 页码: 675-676
作者:  AI Qi-di;  CHEN Chen;  CHU Shi-feng;  ZHANG Zhao;  LUO Yun
收藏  |  浏览/下载:10/0  |  提交时间:2019/12/27


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