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科研机构
海洋研究所 [6]
山东大学 [5]
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中国地质调查局 [2]
中国医学科学院 北京... [2]
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期刊论文 [19]
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2019 [12]
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Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:
Xu, Qi
;
Wu, Ning
;
Li, Xiangqian
;
Guo, Chuanlong
;
Li, Chao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/03/20
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
作者:
Wang, Lijun
;
Guo, Chuanlong
;
Li, Xiuxue
;
Yu, Xuemin
;
Li, Xiangqian
收藏
  |  
浏览/下载:186/0
  |  
提交时间:2019/08/29
Bromophenol-thiazolylhydrazone hybrids
Synthesis
Multifunctional agents
eIF4E/eIF4G interaction
Autophagy
ROS
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice
期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:
Li, Chao
;
Luo, Jiao
;
Guo, Shuju
;
Jia, Xiaoling
;
Guo, Chuanlong
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2019/08/28
type 2 diabetes mellitus
protein tyrosine phosphatase 1B
insulin resistance
hypoglycemic activity
dyslipidemia
Discovery of Natural Dimeric Naphthopyrones as Potential Cytotoxic Agents through ROS-Mediated Apoptotic Pathway
期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 11
作者:
Xu, Kuo
;
Guo, Chuanlong
;
Meng, Jie
;
Tian, Haiying
;
Guo, Shuju
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/08/28
Aspergillus
naphthopyrones
cytotoxicity
endophytic fungus
Leathesia nana
Discovery of Novel Bromophenol Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3051-3067
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Li, Xinxue
;
Wang, Shuaiyu
;
Yu, Xuemin
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  |  
浏览/下载:76/0
  |  
提交时间:2019/08/28
Effects of Quenching Temperature and Cooling Rate on the Microstructure and Mechanical Properties of U75V Rail Steel
期刊论文
Metallography, Microstructure, and Analysis, 2019, 卷号: 8, 期号: 2
作者:
Lan, Yuzhe
;
Zhao, Gang
;
Xu, Yaowen
;
Ye, Chuanlong
;
Zhang, Shaocheng
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Overexpression of Opa interacting protein 5 increases the progression of liver cancer via BMPR2/JUN/CHEK1/RAC1 dysregulation
期刊论文
ONCOLOGY REPORTS, 2019, 卷号: 41, 期号: 4, 页码: 2075-2088
作者:
Li, Yuwen
;
Xiao, Fei
;
Li, Wenting
;
Hu, Pingping
;
Xu, Ruirui
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/11
cell cycle
cell apoptosis
cell growth
liver cancer
Opa interacting
protein 5
Discovery of Novel Bromophenol Thiosemicarbazone Hybrids as Potent Selective Inhibitors of Poly(ADP-ribose) Polymerase-1 (PARP-1) for Use in Cancer
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 6, 页码: 3051-3067
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Li, Xinxue
;
Wang, Shuaiyu
;
Yu, Xuemin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/11
Discovery of Natural Dimeric Naphthopyrones as Potential Cytotoxic Agents through ROS-Mediated Apoptotic Pathway
期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4
作者:
Xu, Kuo
;
Guo, Chuanlong
;
Meng, Jie
;
Tian, Haiying
;
Guo, Shuju
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
Aspergillus
naphthopyrones
cytotoxicity
endophytic fungus
Leathesia
nana
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
作者:
Wang, Lijun
;
Guo, Chuanlong
;
Li, Xiuxue
;
Yu, Xuemin
;
Li, Xiangqian
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/12/11
Bromophenol-thiazolylhydrazone hybrids
Synthesis
Multifunctional
agents
eIF4E/eIF4G interaction
Autophagy
ROS
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