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浏览/检索结果: 共18条，第1-10条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Targeting the hydrophobic channel of NNIBP: discovery of novel 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs with high potency against wild-type and K103N mutant virus 期刊论文 ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 12, 页码: 3202-3217 作者:  Zhou, Zhongxia;  Liu, Tao;  Wu, Gaochan;  Kang, Dongwei;  Fu, Zhipeng 收藏  |  浏览/下载：11/0  |  提交时间：2019/12/11 Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors 期刊论文 RSC ADVANCES, 2019, 卷号: 9, 期号: 50, 页码: 28961-28986 作者:  Jiang, Xiangyi;  Wu, Gaochan;  Zalloum, Waleed A.;  Meuser, Megan E.;  Dick, Alexej 收藏  |  浏览/下载：13/0  |  提交时间：2019/12/11 Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors by exploring the structure-activity relationship of solvent-exposed regions I 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 4, 页码: 430-437 作者:  Kang, Dongwei;  Wang, Zhao;  Chen, Meng;  Feng, Da;  Wu, Gaochan 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/11 DAPY  HIV-1  NNRTIs  solvent-exposed region I  thiophene[3  2-d]pyrimidine   Contemporary medicinal-chemistry strategies for the discovery of selective butyrylcholinesterase inhibitors 期刊论文 DRUG DISCOVERY TODAY, 2019, 卷号: 24, 期号: 2, 页码: 629-635 作者:  Jing, Lanlan;  Wu, Gaochan;  Kang, Dongwei;  Zhou, Zhongxia;  Song, Yuning 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/11 Identification of Dihydrofuro[3,4-d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 3, 页码: 1484-1501 作者:  Kang, Dongwei;  Zhang, Heng;  Wang, Zhao;  Zhao, Tong;  Ginex, Tiziana 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11 Recent applications of click chemistry in drug discovery 期刊论文 EXPERT OPINION ON DRUG DISCOVERY, 2019, 卷号: 14, 期号: 8, 页码: 779-789 作者:  Jiang, Xiangyi;  Hao, Xia;  Jing, Lanlan;  Wu, Gaochan;  Kang, Dongwei 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 CuAAC  Click chemistry  Medicinal chemistry  Drug design  Bioorthogonal  reactions   Identification of Dihydrofuro[3,4-d]pyrimidine Derivatives as Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties. 期刊论文 Journal of medicinal chemistry, 2019 作者:  Kang Dongwei;  Zhang Heng;  Wang Zhao;  Zhao Tong;  Ginex Tiziana 收藏  |  浏览/下载：15/0  |  提交时间：2019/12/13 Identification of Dihydrofuro[3,4-d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties 期刊论文 Journal of Medicinal Chemistry, 2019, 卷号: Vol.62 No.3, 页码: 1484-1501 作者:  Dongwei Kang;  Heng Zhang;  Zhao Wang;  Tong Zhao;  Tiziana Ginex 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17 Design, synthesis and biological evaluation of tacrine-1,2,3-triazole derivatives as potent cholinesterase inhibitors 期刊论文 MEDCHEMCOMM, 2018, 卷号: 9, 期号: 1, 页码: 149-159 作者:  Wu, Gaochan;  Gao, Yun;  Kang, Dongwei;  Huang, Boshi;  Huo, Zhipeng 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/11 Current insights into anti-HIV drug discovery and development: a review of recent patent literature (2014-2017) 期刊论文 EXPERT OPINION ON THERAPEUTIC PATENTS, 2018, 卷号: 28, 期号: 4, 页码: 299-316 作者:  Zuo, Xiaofang;  Huo, Zhipeng;  Kang, Dongwei;  Wu, Gaochan;  Zhou, Zhongxia 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11 HIV-1  AIDS  inhibitors  drug design  medicinal chemistry  hit-to-lead  optimization